Results 51 to 60 of about 2,649 (196)

A broadly applicable method to characterize large DNA viruses and adenoviruses based on the DNA polymerase gene

Virology Journal, 2006
Background Many viral pathogens are poorly characterized, are difficult to culture or reagents are lacking for confirmatory diagnoses. We have developed and tested a robust assay for detecting and characterizing large DNA viruses and adenoviruses.
Montgomery Roy D, Vasquez-Lee Marcia, Rudis Mary R, Hanson Larry A   +3 more
doaj   +1 more source

Oral Inoculation of Chickens with a Candidate Fowl Adenovirus 9 Vector [PDF]

Clinical and Vaccine Immunology, 2013
ABSTRACTFowl adenoviruses (FAdVs) are a potential alternative to human adenovirus-based vaccine vectors. Our previous studies demonstrated that a 2.4-kb region at the left end of the FAdV-9 genome is nonessential for virus replication and is suitable for the insertion or replacement of transgenes. Ourin vivostudy showed that the virus FAdV-9Δ4, lacking
Li, Deng, Shayan, Sharif, Eva, Nagy
openaire   +2 more sources

Pathogenicity and Molecular Typing of Fowl Adenovirus-Associated With Hepatitis/Hydropericardium Syndrome in Central China (2015–2018)

Frontiers in Veterinary Science, 2020
In central China, a large number of broiler and layer flocks have suffered from outbreaks of severe hepatitis/hydropericardium syndrome (HHS). This resulted in huge economic losses to the poultry industry, from 2015 to 2018.
Jin Cui, Jin Cui, Jin Cui, Jin Cui, Yingying Xu, Zutao Zhou, Zutao Zhou, Zutao Zhou, Qingrong Xu, Qingrong Xu, Qingrong Xu, Jiaxiang Wang, Yuncai Xiao, Yuncai Xiao, Yuncai Xiao, Zili Li, Zili Li, Zili Li, Dingren Bi, Dingren Bi, Dingren Bi   +20 more
doaj   +1 more source

Biology of fowl adenovirus type 1 infection of heterologous cells [PDF]

Archives of Virology, 2012
The JM1/1 strain of fowl adenovirus (FAV) serotype 1 isolated from gizzard erosion was used to investigate the biology of FAV in homologous (susceptible) and heterologous cells. The FAV JM1/1 strain is capable of efficient multiplication in primary chicken kidney (CK) cells, but not in Crandell-Rees feline kidney (CRFK) cells or Vero cells.
Taharaguchi, Satoshi, Fukazawa, Rina, Kitazume, Miho, Harima, Hayato, Taira, Kensuke, Oonaka, Kenji, Hara, Motonobu   +6 more
openaire   +2 more sources

Rapid Quantification of Bacteriophages of Mycobacterium spp. and Related Genera in Aquatic Systems

Environmental Microbiology, Volume 28, Issue 6, June 2026.
Two qPCR assays (SYBR Green and TaqMan) targeting the major capsid protein gene of Myoviridae phages infecting Mycobacterium, Rhodococcus and Gordonia spp. were developed and optimised, enabling sensitive detection of these phages in freshwater systems.
Hanieh Shakeri Moghaddam, S. Jane Fowler
wiley   +1 more source

Pathogenicity and Complete Genome Characterization of Fowl Adenoviruses Isolated from Chickens Associated with Inclusion Body Hepatitis and Hydropericardium Syndrome in China. [PDF]

PLoS ONE, 2015
In this study, we determined and genetically characterized three fowl adenoviruses isolated from chickens with inclusion body hepatitis (IBH) and hydropericardium syndrome (HPS) in China and assessed their pathogenicity.
Jing Zhao, Qi Zhong, Ye Zhao, Yan-xin Hu, Guo-zhong Zhang   +4 more
doaj   +1 more source

Prevalence and Molecular Characteristics of FAdV-4 from Indigenous Chicken Breeds in Yunnan Province, Southwestern China

Microorganisms, 2023
Fowl adenovirus-induced hepatitis–pericardial effusion syndrome outbreaks have been increasingly reported in China since 2015, resulting in substantial economic losses to the poultry industry.
Jinyu Lai, Liangyu Yang, Fashun Chen, Xingchen He, Rongjie Zhang, Yong Zhao, Gan Gao, Weiwu Mu, Xi Chen, Shiyu Luo, Tao Ren, Bin Xiang   +11 more
doaj   +1 more source

Advances in the Treatment of Sensorineural Hearing Loss: From Traditional Therapies to Stem Cell and Gene Therapies

Advanced Sensor Research, Volume 5, Issue 4, April 2026.
Sensorineural hearing loss (SNHL) occurs in 1.5 billion globally, primary driven by damage of cochlear hair cells and spiral ganglion neurons. This review systematically examines current therapeutic strategies for sensorineural hearing loss, including traditional drug and physical therapies as well as emerging stem cell and gene therapies, providing a ...
Ruirui Chen, Yang Zhang, Zhe Li, Renjie Chai   +3 more
wiley   +1 more source

Transcriptome analysis of fowl adenovirus serotype 4 infection in chickens [PDF]

Virus Genes, 2019
Fowl adenovirus serotype 4 (FAdV-4) is a causative agent of inclusion body hepatitis and hydropericardium-hepatitis syndrome. These diseases cause considerable economic losses in the global poultry industry and are significant stressors for infected chickens. However, the molecular mechanisms of FAdV-4 pathogenesis are poorly understood. In the present
Ren, Guangcai, Wang, Han, Huang, Miaorong, Yan, Yuanyuan, Liu, Fan, Chen, Ruiai   +5 more
openaire   +2 more sources

From Lake Victoria to the Tap: Antibiotic Resistance and Pathogenic Contamination of Kisumu City Water Supply and Wastewater Network

Tropical Medicine &International Health, Volume 31, Issue 4, Page 547-559, April 2026.
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Oleg N. Reva, Anthony Sifuna, Francis Orata, Caroline Omolo, Jacob Stanley Iramiot, Mark C. Enright, Awelani Mutshembele, Jian Zhou, William A. Shivoga   +8 more
wiley   +1 more source