Results 191 to 200 of about 74,948 (336)

Alleviating experimental pulmonary hypertension via co-delivering FoxO1 stimulus and apoptosis activator to hyperproliferating pulmonary arteries

, 2022
Bingbing Li, Chao Teng, Huiling Yu, Xiaohong Jiang, Xuyang Xing, Qi Jiang, Chenshi Lin, Zongmin Zhao, Ruifeng Zhang, Wei He   +9 more
openalex   +1 more source

Intermediate monocytes induced by IFN-γ inhibit cancer metastasis by promoting NK cell activation through FOXO1 and interleukin-27 [PDF]

, 2022
Rikang Wang, Weili Bao, Mouli Pal, Yunfeng Liu, Karina Yazdanbakhsh, Hui Zhong   +5 more
openalex   +1 more source

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen, Zhenzhen Wang, Liqiang Song, Qianqian Chen, Hang Zhang, Tao Pan, Jianli Pan, Sheng Zhao, Ting Shang, Hong'en Xu, Xing Lv, Jing Li, Fei Kang, Yongzhan Nie, Feng Zhao, Lei Shi, Zheng Wang   +16 more
wiley   +1 more source

Evaluating serum FOXs transcription factor proteins in Hashimoto’s thyroiditis: a comparative analysis

Türk Biyokimya Dergisi
Hashimoto’s thyroiditis (HT) is a complex metabolic autoimmune disease. FOXs participate in many cellular metabolic processes and control many related genes. This study aimed to investigate FOXO1, FOXP1 and FOXP2 protein levels in HT disease.
Agbektas Tugba, Zontul Cemile, Tuncbilek Zuhal, Tas Ayca, Zirek Merve, Sariakcali Baris, Silig Yavuz   +6 more
doaj   +1 more source

Colorectal cancer cell-derived CCL20 recruits regulatory T cells to promote chemoresistance via FOXO1/CEBPB/NF-κB signaling [PDF]

, 2019
Dan Wang, Yang Li, Weina Yu, Qian Wu, Jingyao Lian, Feng Li, Shasha Liu, Aitian Li, Zhiang He, Jinbo Liu, Zhenqiang Sun, Weitang Yuan, Yi Zhang   +12 more
openalex   +1 more source

Deoxyshikonin inhibited rotavirus replication by regulating autophagy and oxidative stress through SIRT1/FoxO1/Rab7 axis

, 2023
Haohai Huang, Dan Liao, Bin He, Rong Pu, Yejia Cui, Guanghui Zhou   +5 more
openalex   +1 more source

Cidea Targeting Protects Cochlear Hair Cells and Hearing Function From Drug‐ and Noise‐Induced Damage

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang, Ruiying Qiang, Yuan Zhang, Jinxian Wan, Chen Tao, Ying Dong, Xujun Tang, Li Xu, Hairong Xiao, Yanqin Lin, Wei Tong, Ying Ma, Yongming Wang, Peng Li, Renjie Chai   +14 more
wiley   +1 more source

Hepatocyte FoxO1 Deficiency Protects From Liver Fibrosis via Reducing Inflammation and TGF-β1-mediated HSC ActivationSummary

Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: The O-class of the forkhead transcription factor FoxO1 is a crucial factor mediating insulin→PI3K→Akt signaling and governs diverse cellular processes.
Quan Pan, Mingming Gao, DaMi Kim, Weiqi Ai, Wanbao Yang, Wen Jiang, Wesley Brashear, Yujiao Dai, Sha Li, Yuxiang Sun, Yajuan Qi, Shaodong Guo   +11 more
doaj   +1 more source

Uncovering the MET-TRIB3-FOXO1 axis: A novel target in MET-driven hepatocellular carcinoma: Editorial on “MET promotes hepatocellular carcinoma development through the promotion of TRIB3-mediated FOXO1 degradation” [PDF]

Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +3 more
openalex   +1 more source

Supplementary Figure 7 from Overexpression of GOLPH3 Promotes Proliferation and Tumorigenicity in Breast Cancer via Suppression of the FOXO1 Transcription Factor

, 2023
Zhao-Lei Zeng, Huan‐Xin Lin, Xiaohui Zhao, Guanglin Liu, Xi Wang, Rui‐Hua Xu, Kun Chen, Jun Li, Libing Song   +8 more
openalex   +1 more source