Results 81 to 90 of about 74,948 (336)
PeerJ, 2022 Background Steroid-induced osteonecrosis of the femoral head (SONFH) is a disorder that causes severe disability in patients and has a high incidence worldwide.
Fei Sun +4 more
semanticscholar +1 more source
Breast Cancer: Targets and Therapy, 2023 Jinling Yu,1 Haofeng Wang,1 Weida Shen,1 Yingzi Zhou,2 Jing Cui,1 Haichuan Li,3 Beimin Gao1 1Department of Breast Surgery, Shanghai Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai, 200050, People’s Republic of China;
Yu J +6 more
doaj
Trichostatin A activates FOXO1 and induces autophagy in osteosarcoma
Archives of Medical Science, 2018 Introduction Histone deacetylase inhibitors (HDACIs) inhibit human osteosarcoma growth and cause apoptosis. Previously, we reported that HDACIs induce autophagy via the FOXO1 pathway.
Yunjuan Bai +8 more
doaj +1 more source
Advances in Laboratory Medicine, 2023 La enfermedad hepática crónica y sus complicaciones, la cirrosis y el carcinoma hepatocelular, presentan una elevada mortalidad. Los tratamientos curativos, como la hepatectomía parcial o el trasplante hepático, tienen una aplicación limitada en ...
Fernández-Galán Esther +10 more
doaj +1 more source
Development of a targeted and controlled nanoparticle delivery system for FoxO1 inhibitors [PDF]
, 2020 Background: Poly (lactic-co-glycolic acid) (PLGA) and polyethylene glycol (PEG) are polymers approved by the United States’ Food and Drug Administration.
Cheng, Zhiyong +5 more
core +1 more source
miR-181a increases FoxO1 acetylation and promotes granulosa cell apoptosis via SIRT1 downregulation. [PDF]
, 2017 Oxidative stress impairs follicular development by inducing granulosa cell (GC) apoptosis, which involves enhancement of the transcriptional activity of the pro-apoptotic factor Forkhead box O1 (FoxO1).
Ding, Lijun +10 more
core +2 more sources
Role of Forkhead Box Protein O1 (FoxO1) in Stroke: A Literature Review
Aging and Disease, 2022 Stroke is one of the most prevalent causes of death around the world. When a stroke occurs, many cellular signaling cascades and regulators are activated, which results in severe cellular dysfunction and debilitating long-term disability.
Sichao Guo +4 more
semanticscholar +1 more source
Unspliced XBP1 controls autophagy through FoxO1 [PDF]
Cell Research, 2013 Protein homeostasis in higher eukaryotes is balanced by a dynamic network of adaptive mechanisms, including the unfolded protein response (UPR) and autophagy. In a paper recently published in Cell Research, Zhu and co-workers uncover a novel biological function of the unspliced form of the UPR transcription factor XBP1 in the modulation of autophagy ...
Vidal, Rene L., Hetz Flores, Claudio
openaire +3 more sources
The correlation of the forkhead transcription factor foxo1 expression and histopathological pancreatic lesions in dogs [PDF]
Iraqi Journal of Veterinary SciencesThe objective of the current research was to characterize the correlation of Forkhead transcription factor and histopathologic findings of dogs’ pancreatic lesions.
Firas M. Abed +4 more
doaj +1 more source
Advances in Laboratory Medicine, 2023 Chronic liver disease and related complications, cirrhosis and hepatocellular carcinoma, are associated with high mortality. Curative treatments, partial hepatectomy or liver transplantation, have limited applicability in patients with cirrhosis due to ...
Fernández-Galán Esther +10 more
doaj +1 more source