Results 301 to 310 of about 199,492 (387)
Local T-Cell Dysregulation and Immune Checkpoint Expression in Human Papillomavirus-Mediated Recurrent Respiratory Papillomatosis. [PDF]
CellsEckel HNC, Lyu SI, Faste F, Sharma SJ, Nobis A, Wuerdemann N, Ziogas M, Mayer M, Suchan MC, Wennhold K, Garcia-Marquez MA, Thelen M, Hagen E, Eßer J, Klasen C, Siefer O, Otte M, Schloesser HA, Klussmann JP, Quaas A, Hansen KK. +20 moreeuropepmc +1 more sourceTumor desialylation surpasses anti‐PD‐L1 checkpoint therapy in restoring anti‐tumor immunity in a murine model for colorectal cancer
International Journal of Cancer, EarlyView.What's New?
Our research highlights how tumor sialylation affects tumor growth and reshapes the immune tumor microenvironment in colorectal cancer. We demonstrate for the first time that complete removal of sialic acids from colorectal tumor cells elicits a robust anti‐tumor immune response, but does not enhance anti‐PD‐L1 blockade efficacy.Irene van der Haar Àvila, Tao Zhang, Victor Lorrain, Eelco Keuning, Laraib Amir Ali, Cora Chadick, Sara García‐García, Louis Boon, Noortje de Haan, Juan J. García‐Vallejo, Yvette van Kooyk, Sandra J. van Vliet +11 morewiley +1 more sourceIDO1-AhR axis increases T regulatory cells in <i>Plasmodium vivax</i> malaria infection. [PDF]
Front ImmunolDos Santos RO, Carvalho NO, de Morais TBDN, Sobrinho WBS, da Cruz MGS, de Faria ES, de Araújo FF, Magalhães VP, Lopes SCP, Malheiros A, da Mota AJ, Santiago HDC, Nogueira PA, Teixeira de Carvalho A, de Lacerda MVG, Lalwani P. +15 moreeuropepmc +1 more sourceSingle‐cell sequencing reveals the role of IL‐33+ endothelial subsets in promoting early gastric cancer progression
iMeta, EarlyView.A single‐cell atlas was established to reveal the molecular characteristics of early gastric cancer (EGC). In combination with organoids, animal models, and clinical samples, it was found that subpopulations such as pit mucous‐like cell (PMC‐like), proliferating cell (PC), CH25H+ CD4+ T cell, IL‐33+ endothelial cell, and ADAMTSL2+ endothelial cell are ...Li Zhou, Mei Yang, Chao Deng, Manqiu Hu, Suhua Wu, Kewen Lai, Lili Zhang, Zhiji Chen, Qin Tang, Qingliang Wang, Lu Chen, Runmin Zha, Yuanyuan Chen, Yibo Tan, Song He, Zhihang Zhou +15 morewiley +1 more sourceCalcineurin Inhibitors, but not Rapamycin, Reduce Percentages of CD4+CD25+FOXP3+ Regulatory T Cells in Renal Transplant Recipients
, 2006 David San Segundo, Juan Carlos Ruiz, María Jesús Izquierdo, Gema Fernández‐Fresnedo, C. Gómez-Alamillo, Ramón Merino, M.J. Benito, Eva Cacho, Emilio Rodrigo, R. Palomar, Marcos López‐Hoyos, Manuel Arias +11 moreopenalex +1 more sourceGut microbiota and tuberculosis
iMeta, EarlyView.This review explores the intricate relationship between gut microbiota (GM) and tuberculosis (TB). The figure illustrates the bidirectional effects between GM dynamics and TB progression, as well as the interactions between the GM and antituberculosis drugs.Yanhua Liu, Ling Yang, Maryam Meskini, Anjana Goel, Monique Opperman, Sagar Singh Shyamal, Ajay Manaithiya, Meng Xiao, Ruizi Ni, Yajing An, Mingming Zhang, Yuan Tian, Shuang Zhou, Zhaoyang Ye, Li Zhuang, Linsheng Li, Istuti Saraswat, Ankita Kar, Syed Luqman Ali, Shakir Ullah, Syed Yasir Ali, Shradha Kaushik, Tianmu Tian, Mingyang Jiao, Shujun Wang, Giulia Ghisleni, Alice Armanni, Sara Fumagalli, WenYu Wang, Chao Cao, Maria Carpena, Miguel A. Prieto, Antonia Bruno, Chanyuan Jin, Hanqing Hu, Yuhang Zhang, Ilse du Preez, Ashok Aspatwar, Lingxia Zhang, Wenping Gong +39 morewiley +1 more sourcePidotimod alleviated experimental autoimmune encephalomyelitis by regulating the balance of splenic lymphocytes. [PDF]
BMC ImmunolWang Y, Zhang S, Li A, Zhao P, Ma X, Zhang X, Wu J, Qiao Z, Wang C, Lang X, Liu X, Sun B, Li H, Liu Y. +13 moreeuropepmc +1 more source