Results 101 to 110 of about 20,377 (204)

CLINICAL AND DIAGNOSTIC VALUE OF THE DETERMINANTION OF FRACTALKINE IN ATOPIC DERMATITIS OF CHILDREN

open access: yesRUDN Journal of Medicine, 2018
In recent years there has been an increase in the incidence of atopic dermatitis in children. However, despite numerous studies, still remains the problem of objective laboratory diagnosis of this disease, and, respectively, rational pharmacotherapy. Aim.
M M Ben   +2 more
doaj   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu   +5 more
wiley   +1 more source

A guide to chemokines and their receptors [PDF]

open access: yes, 2018
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that signal through cell surface G‐protein coupled heptahelical chemokine receptors.
Braun A   +11 more
core   +1 more source

Spermatozoal Fractalkine Signaling Pathway Is Upregulated in Subclinical Varicocele Patients with Normal Seminogram and Low-Level Leucospermia

open access: yesAdvances in Urology, 2017
Background. Fractalkine is produced in seminal plasma in small amounts and correlates with sperm motility. Purpose. To investigate the possible effect of low-level leucospermia on spermatozoa oxidative stress and sDNA fragmentation in patients with ...
Salwa M. Abo El-khair   +4 more
doaj   +1 more source

Cx3cr1-deficient microglia exhibit a premature aging transcriptome. [PDF]

open access: yes, 2019
CX3CR1, one of the highest expressed genes in microglia in mice and humans, is implicated in numerous microglial functions. However, the molecular mechanisms underlying Cx3cr1 signaling are not well understood.
Allaire, Norm   +15 more
core  

FRACTALKINE-FRACTALKINE RECEPTOR AXIS IN HUMAN COLORECTAL CANCER

open access: yes, 2012
Although the presence of genetic and epigenetic abnormalities is important for tumor occurrence, the formation of an inflammatory microenvironment plays a pivotal role in tumor progression. Even if the link between cancer and inflammation has been widely accepted in the last decade, no inflammation-associated markers or potential targets have yet been ...
openaire   +2 more sources

FRACTALKINE: PATHOGENIC ROLE AND DIAGNOSTIC CAPABILITIES

open access: yesКубанский научный медицинский вестник, 2017
The review presents modern data on the pathogenic role of CC chemokine is CX3CL1 or fractalkine in the cascade of immune responses in various diseases.
O. A. MESNYANKINA   +2 more
doaj   +1 more source

A human macrophage – hepatocyte co-culture model for comparative studies of infection and replication of Francisella tularensis LVS strain and subspecies holarctica and mediasiatica [PDF]

open access: yes, 2016
Detection of intracellular LPS in macrophage / hepatocyte co-cultures infected with LVS (open bars), spp. holarctica (grey filled bars) or spp. mediasiatica (black filled bars) and untreated control (hatched bars).
Alexander S. Mosig   +5 more
core   +3 more sources

Bibliometric profile of neurogenic bladder in the literature: a 20-year bibliometric analysis

open access: yesNeural Regeneration Research, 2015
Neurogenic bladder is a dysfunction of the lower urinary tract caused by nervous system disorder. We investigated the trends in publication of articles under the topic "neurogenic bladder" using bibliometric analysis.
Yuan Gao   +7 more
doaj   +1 more source

Acupuncture and vitamin B12 injection for Bell′s palsy: no high-quality evidence exists

open access: yesNeural Regeneration Research, 2015
OBJECTIVE: To assess the efficacy of acupuncture combined with vitamin B 12 acupoint injection versus acupuncture alone to reduce incomplete recovery in patients with Bell′s palsy.
Li-li Wang   +4 more
doaj   +1 more source

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