Results 181 to 190 of about 20,377 (204)

Fractalkine and vascular injury

Trends in Immunology, 2001
The vascular endothelium plays a central role in the recruitment and migration of circulating effector cells into sites of inflammation and immune responses. The unique CX(3)C-chemokine, fractalkine, is expressed on activated endothelial cells, and its receptor, CX(3)CR1, is expressed on natural killer cells, monocytes and some CD8+ T cells, all of ...
H, Umehara, E, Bloom, T, Okazaki, N, Domae, T, Imai   +4 more
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Fractalkine/CX3CR1 and atherosclerosis

Clinica Chimica Acta, 2011
Fractalkine is a unique chemokine which has both adhesive and chemoattractant functions. With the increasing emphasis on the importance of inflammation in atherosclerosis, more attention has been focused on the role of chemokines in atherosclerosis.
Hong, Liu, Deqian, Jiang
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Fractalkine and fractalkine receptors in human neurons and glial cells

Journal of Neuroscience Research, 2002
AbstractFractalkine has been identified as a novel chemokine that exhibits cell adhesion and chemoattractive properties in the central nervous system (CNS), and the fractalkine receptors, CX3CR1, are also expressed in the CNS. In the present study, the expression of fractalkine and fractalkine receptors was investigated in enriched populations of human
Kozo, Hatori, Atsushi, Nagai, Rochelle, Heisel, Jae K, Ryu, Seung U, Kim   +4 more
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Human keratinocytes express fractalkine/CX3CL1

Journal of Dermatological Science, 2003
fractalkine/CX3CL1 is a unique chemokine that has properties of both chemoattractants and adhesion molecules. The major source of this chemokine in the skin is still controversial.studies were undertaken to determine the expression of fractalkine in human skin.RT-PCR, Western blotting, and immunostaining were performed with normal human epidermal ...
Makoto, Sugaya, Koichiro, Nakamura, Hiroshi, Mitsui, Tomonori, Takekoshi, Hidehisa, Saeki, Kunihiko, Tamaki   +5 more
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Fractalkine in human inflammatory cardiomyopathy

Heart, 2011
Background Cardiac inflammation is important for the prognosis of patients with inflammatory cardiomyopathy (CMi), but the mechanisms leading to it are not fully elucidated. Objective To study the role of fractalkine (CX3CL1) in chemotactic and ...
F, Escher, R, Vetter, U, Kühl, D, Westermann, H-P, Schultheiss, C, Tschöpe   +5 more
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Fractalkine/CX3CL1 in rheumatoid arthritis

Modern Rheumatology, 2016
Fractalkine is a CX3C chemokine that exists in both membrane-bound and soluble forms. Interaction between fractalkine and its unique receptor (CX3CR1) induces cell adhesion, chemotaxis, crawling, "accessory cell" activity, and survival. The serum level of fractalkine is elevated in patients with rheumatoid arthritis (RA) and is correlated with disease ...
Toshihiro, Nanki, Toshio, Imai, Shinichi, Kawai   +2 more
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Fractalkine expression in human renal inflammation

The Journal of Pathology, 2001
AbstractImmune and inflammatory human renal disease is associated with heavy mononuclear cell infiltration. The trafficking of these cells to extravascular sites is directed by local production of chemokines. Fractalkine is the first described cell‐surface anchored chemokine and has potent mononuclear cell‐directed adhesion and chemotactic properties ...
Paul, Cockwell, Srabasti J, Chakravorty, John, Girdlestone, Caroline O S, Savage   +3 more
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Increase of serum fractalkine and fractalkine gene expression levels in sickle cell disease patients

International Journal of Hematology, 2014
In the present study, we examined the role of fractalkine (Fkn), a member of the chemokine family, in the pathogenesis of sickle cell disease (SCD). Eighty-seven children with sickle cell disease and 55 healthy children were enrolled in the study. Complete blood counts, serum levels of C-reactive protein, tumor necrosis factor-α, interferon-γ and ...
Selma, Unal, Ozlem, Ozdemir, Ahmet Ata, Ozcimen, Yesim, Oztas   +3 more
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Fractalkine receptor polymorphism and chronic tonsillitis

European Archives of Oto-Rhino-Laryngology, 2014
The objective of this study is to examine whether there is an association of fractalkine gene receptor polymorphisms with chronic tonsillitis. This is a cross-sectional study in the setting of a tertiary referral center. The study group included 79 patients with chronic tonsillitis and 76 controls without history of chronic tonsillitis.
Seda Turkoglu, Babakurban, Selim S, Erbek, Yunus Kasim, Terzi, Fatih, Arslan, Feride I, Sahin   +4 more
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Fractalkine in obstructive sleep apnea patients

Sleep and Breathing, 2016
Obstructive sleep apnea (OSA) is the most common sleep disorder affecting 2-4 % of the adult population. In addition to several potential mechanisms, inflammation is one of the suggested etiological factors in OSA. Fractalkine/CX3CL1 which is detected in activated or stressed endothelium, smooth muscle cells, skeletal muscle cells, macrophages, neurons,
Gulgun Cetintas, Afsar, Ozlem, Oruc, Sema, Sarac, Özgür Bilgin, Topçuoğlu, Cuneyt, Salturk, Fatma Merve, Tepetam, Ismet, Bulut   +6 more
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