Results 31 to 40 of about 20,377 (204)
Metalloprotease Dependent Release of Placenta Derived Fractalkine
Mediators of Inflammation, 2014 The chemokine fractalkine is considered as unique since it exists both as membrane-bound adhesion molecule and as shed soluble chemoattractant. Here the hypothesis was tested whether placental fractalkine can be shed and released into the maternal ...
Monika Siwetz +6 more
doaj +1 more source
Influence of a Concurrent Exercise Training Intervention during Pregnancy on Maternal and Arterial and Venous Cord Serum Cytokines: The GESTAFIT Project [PDF]
, 2019 The aim of the present study was to analyze the influence of a supervised concurrent exercise-training program, from the 17th gestational week until delivery, on cytokines in maternal (at 17th and 35th gestational week, and at delivery) and arterial and ...
Acosta-Manzano, Pedro +10 more
core +5 more sources
Fractalkine and inflammatory diseases
Japanese Journal of Clinical Immunology, 2005 The migration of leukocytes into inflamed peripheral tissues and lymphoid organs involves a cascade of molecular events finely regulated by cell adhesion molecules and chemokines. Fractalkine/CX3CL1 is a membrane-bound chemokine that functions not only as a chemoattractant but also as an adhesion molecule, and is expressed on endothelial cells ...
Toshio, Imai +3 more
openaire +3 more sources
Fractalkine/CX3CR1 signaling during neuropathic pain [PDF]
Frontiers in Cellular Neuroscience, 2014 Chronic pain represents a major problem in clinical medicine. Whilst the acute pain that is associated with tissue injury is a protective signal that serves to maintain homeostasis, chronic pain is a debilitating condition that persists long after the inciting stimulus subsides.
Clark, Anna K., Malcangio, Marzia
openaire +4 more sources
Targeting neuroinflammation in Alzheimer’s disease [PDF]
, 2016 Almost 47 million people suffer from dementia worldwide, with an estimated new case diagnosed every 3.2 seconds. Alzheimer’s disease (AD) accounts for approximately 60%–80% of all dementia cases. Given this evidence, it is clear dementia represents one
Bronzuoli, MARIA ROSANNA +3 more
core +1 more source
Neuroprotective fractalkine in fetal alcohol syndrome [PDF]
American Journal of Obstetrics and Gynecology, 2011 Neuroprotective peptides (NAP+SAL) can prevent some alcohol-induced damage in fetal alcohol syndrome(FAS). Fractalkine, a chemokine constitutively expressed in the CNS reduces neuronal death from activated microglia. Using a model of FAS we evaluated if fractalkine is altered and if NAP+SAL work through fractalkine.Using a FAS model, C57BL6/J-mice were
Robin, Roberson +4 more
openaire +2 more sources
Mediators of Inflammation, 2015 Introduction. Fractalkine is a chemokine associated with atherosclerosis. Increased serum levels have been reported in unstable coronary artery disease (CAD) and to predict mortality in heart failure.
Kristian Laake +5 more
doaj +1 more source
PLoS Pathogens, 2009 While most chemokine receptors fail to cross the chemokine class boundary with respect to the ligands that they bind, the human cytomegalovirus (HCMV)-encoded chemokine receptor US28 binds multiple CC-chemokines and the CX(3)C-chemokine Fractalkine. US28
Jennifer Vomaske +10 more
doaj +1 more source
Modulation of adult-born neurons in the inflamed hippocampus. [PDF]
, 2013 Throughout life new neurons are continuously added to the hippocampal circuitry involved with spatial learning and memory. These new cells originate from neural precursors in the subgranular zone of the dentate gyrus, migrate into the granule cell layer,
Belarbi, Karim, Rosi, Susanna
core +2 more sources
Fractalkine Attenuates Microglial Cell Activation Induced by Prenatal Stress
Neural Plasticity, 2016 The potential contribution of inflammation to the development of neuropsychiatric diseases has recently received substantial attention. In the brain, the main immune cells are the microglia.
Joanna Ślusarczyk +6 more
doaj +1 more source