Results 41 to 50 of about 20,377 (204)

Dynamics of fractalkine among Kharkiv residents with different body mass

Mìžnarodnij Endokrinologìčnij Žurnal, 2017
Background. When developing individual approaches to treating obesity and comorbid diseases, the presence and severity of inflammation in adipose tissue should be taken into account, as it significantly affects its metabolism and secretion.
K.V. Misiura, P.P. Kravchun
doaj   +1 more source

Investigation of Fractalkine and MIP-1β Levels as Markers in Premature Membrane Rupture Cases: A Prospective Cohort Study

Clinical and Experimental Obstetrics & Gynecology, 2023
Background: To investigate fractalkine and MIP-1β levels in amniotic fluid and serum of cases with premature rupture of membranes. Methods: In this prospective cohort study, pregnant women who applied to the Firat University, Gynecology and Obstetrics ...
Şehmus Pala, Remzi Atılgan, Bünyamin Çim, Mehmet Kağan Açıkgözoğlu, Meryem Demir Can, Süleyman Cemil Oğlak, Nevin İlhan, Mustafa Yılmaz   +7 more
doaj   +1 more source

Diesel Exhaust Activates & Primes Microglia: Air Pollution, Neuroinflammation, & Regulation of Dopaminergic Neurotoxicity [PDF]

, 2011
BACKGROUND: Air pollution is linked to central nervous system disease, but the mechanisms responsible are poorly understood. OBJECTIVES: Here, we sought to address the brain-region-specific effects of diesel exhaust (DE) and key cellular mechanisms ...
Block, Michelle L, Duke, Laura, Johnson, Jo Anne, Kodavanti, Prasada, Kodavanti, Urmila, Levesque, Shannon, Lull, Melinda E., Stadler, Krisztian, Surace, Michael J., Taetzsch, Thomas, Wagner, Alison   +10 more
core   +1 more source

The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis. [PDF]

, 2017
We recently found that integrin αvβ3 binds to fibroblast growth factor (FGF)-αvβ31 (FGF1), and that the integrin-binding defective FGF1 mutant (Arg-50 to glutamic acid, R50E) is defective in signalling and antagonistic to FGF1 signalling. R50E suppressed
Hamada, Yoshinosuke, Hatori, Nobuaki, Kawaguchi, Naomasa, Lam, Kit S, Matsuura, Nariaki, Mori, Seiji, Shih, Tsung-Chieh, Takada, Yoko K, Takada, Yoshikazu, Wu, Chun-Yi, Yamamoto, Hirofumi   +10 more
core   +2 more sources

Fractalkine: A Survivor's Guide [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2012
Chemokines are a family of low-molecular-weight proteins essential to the directed migration of cells under homeostatic and pathological conditions. Fractalkine (CX3CL1) is an unusual chemokine that can act as either a soluble or membrane-bound mediator and signals through the G protein–coupled chemokine receptor CX3CR1, expressed on monocytes, natural
White, G, Greaves, D
openaire   +2 more sources

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Circulating Fractalkine Levels Predict the Development of the Metabolic Syndrome

International Journal of Endocrinology, 2014
The fractalkine/CX3CR1 axis plays an important role in regulating glucose and lipid metabolism. However, the role of fractalkine in metabolic disorders remains to be fully elucidated. We selected 887 Chinese (40–65 years old) at baseline, with a subgroup
Yin Xueyao, Zhang Saifei, Yu Dan, Pan Qianqian, Dong Xuehong, Zhou Jiaqiang, Zheng Fenping, Li Hong   +7 more
doaj   +1 more source

Association of the Fractalkine Level with Non-modifiable and Modifiable Factors of Cardiovascular Risk, the Severity of the Atherosclerotic Lesions of the Coronary Vessels

Львівський клінічний вісник, 2016
The purpose of research is to evaluate the association of fractalkine level with non-modifiable and modifiable factors of cardiovascular risk, and the severity of the atherosclerotic lesions of the coronary arteries. Materials and Methods.
Lopina N.
doaj   +1 more source

Natural Killer Subset Changes and Vascular Endothelial Growth Factor‐A Plasma Profile in Progressive Supranuclear Palsy: The NKscape Study

Movement Disorders, EarlyView.
Abstract Background Emerging evidence implicates neuroinflammation in progressive supranuclear palsy (PSP) pathophysiology, with elevated cyto‐chemokines suggesting natural killer (NK) cell involvement. Methods We characterized peripheral NK in PSP (N = 11) versus Parkinson's disease (PD, N = 10) and healthy controls (HC, N = 8) at both ...
Marina Picillo, Cristina Basile, Francesco Montella, Valentina Lopardo, Mariangela Orlando, Roberta Tarallo, Domenico Palumbo, Viola Melone, Maria Francesca Tepedino, Paolo Barone, Annibale Alessandro Puca, Elena Ciaglia   +11 more
wiley   +1 more source

Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]

, 2004
Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Abdi R, Anders HJ, Anders HJ, Anders HJ, Bruhl H, Burne-Taney MJ, Feng L, Fituri O, Fujinaka H, Garcia GE, Grone HJ, Keane MP, Mack M, Miura M, Murphy PM, Nath KA, Perez de Lema G, Rollins BJ, Romagnani P, Segerer S, Segerer S, Segerer S, Tang WW, Taub DD, Tesch GH, Tokuda A, Topham PS, Vielhauer V, Vielhauer V, Wada T, Wang Y, Wenzel U, Wu X, Wu X, Zernecke A   +34 more
core   +1 more source