Results 81 to 90 of about 20,377 (204)
Introduction : In data based on ex vivo studies and animal models, fractalkine is considered an important mediator in the development and destabilization of atherosclerotic plaques.
Marta Masztalewicz +4 more
doaj +1 more source
Characterization of inflammatory response in acute-on-chronic liver failure and relationship with prognosis [PDF]
ACLF is characterized by a systemic inflammatory response, but the cytokines involved in this process have not been well studied. The aim of this study was to characterize the systemic inflammatory response in patients with cirrhosis and ACLF and its ...
Ariza Piquer, Xavier +13 more
core +1 more source
Strategies for Monitoring Serum Protein Degradation With an Antibody Array‐Based Technology
This study analyzed the stability of 480 proteins in human serum samples collected from 10 healthy donors and incubated at room temperature for 0–48 h. Antibody array profiling revealed significant time‐dependent degradation of 201 proteins. Subsequent physicochemical and functional enrichment analyses demonstrated that the degraded proteins were ...
Yanlin Wang +7 more
wiley +1 more source
Fractalkine: a novel cardiac chemokine? [PDF]
This editorial refers to ‘Detrimental effect of fractalkine on myocardial ischemia and heart failure’ by W. Xuan et al ., pp. 385–393, this issue. The endothelium plays a central role in maintaining cardiovascular integrity, function, and the response to injury.
S E, Altin, P C, Schulze
openaire +2 more sources
Graphene Triggers Inflammation in Murine Microglia via Phagocytosis
Phagocytosis of single‐layer graphene by microglia triggers inflammatory activation without cytotoxicity. Small carbon nanotubes elicit similar responses, whereas larger graphene nanoplatelets do not. Proteomic analysis reveals effects on inflammation, cytoskeleton, and proliferation, highlighting the importance of graphene stability for safe neural ...
Pratika Rai +10 more
wiley +1 more source
The role of the novel Th17 cytokine IL-26 in intestinal inflammation [PDF]
Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human disease is completely unknown. The aim of this study was to analyse its
Auernhammer, Christoph J. +7 more
core +1 more source
A High‐Resolution Transcriptomic Atlas of Cell Types in the Ventral Visual Thalamus
Visual information from the eyes travels from retinal ganglion cells (RGCs) to reach the brain through several relay centers. One of these centers, the ventral lateral geniculate nucleus (vLGN), is much less understood than others. In this study, we created the first detailed map of the different cell types found in the mouse vLGN.
Katelyn Stebbins +5 more
wiley +1 more source
The impact of MFG-E8 in chronic pancreatitis: potential for future immunotherapy?
Background The glycoprotein MFG-E8 mediates phagocytic clearance of apoptotic cells and influences the pathogenesis and progression of inflammatory diseases.
D’Haese Jan G +10 more
doaj +1 more source
Basal adenosine modulates the functional properties of AMPA receptors in mouse hippocampal neurons through the activation of A1R A2AR and A3R [PDF]
Adenosine is a widespread neuromodulator within the CNS and its extracellular level is increased during hypoxia or intense synaptic activity, modulating pre- and postsynaptic sites.
BERTOLLINI, Cristina +7 more
core +1 more source
This systematic review and meta‐analysis, which examined the effects of acute endurance training on immunoregulatory myokines, showed significant small‐moderate to very large positive effect sizes for IL‐6, IL‐10, IL‐1ra, IL‐8, IL‐15, and TNF‐α. These effects were significantly moderated by risk of bias, sex, age, V̇O2peak, experience, type of exercise,
Miriam Ringleb +5 more
wiley +1 more source

