Results 81 to 90 of about 210,852 (219)

A Discrete Method Based on the CE-SE Formulation for the Fractional Advection-Dispersion Equation

Discrete Dynamics in Nature and Society, 2015
We obtain a numerical algorithm by using the space-time conservation element and solution element (CE-SE) method for the fractional advection-dispersion equation. The fractional derivative is defined by the Riemann-Liouville formula. We prove that the CE-
Silvia Jerez, Ivan Dzib
doaj   +1 more source

Fractional-order elements of complement order

, 2020
The design of analogue fractional-order systems requires the presence of fractional-order elements (FOEs), capacitive and/or inductive, featuring fractional order α (0 < α < 1). As currently FOEs are not available as discrete elements, suitable RC networks are used to overcome this obstacle.
Koton J., Herencsar N., Kubanek D., Psychalinos C.   +3 more
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

On new systems of rabies virus using vaccination variable with modification

MethodsX
Usually, a compartmental epidemiological modeling such as the SIR (Susceptible-Infectious-Recovered) or SEIR (Susceptible-Exposed-Infectious-Recovered) model must be modified in order to include a vaccine element in a mathematical representation of ...
Ibtehal Alazman
doaj   +1 more source

Enhance limit cycle oscillation in a wind flow energy harvester system with fractional order derivatives

Theoretical and Applied Mechanics Letters, 2014
Advances in material science and mathematics in conjunction with technological needs have triggered the use of material and electric components with fractional order physical properties. This paper considers the mathematical model of a piezoelectric wind
Cedrick A. Kitio Kwuimy, Grzegorz Litak
doaj   +1 more source

A Creep Model of Asphalt Mixture Based on Variable Order Fractional Derivative

Applied Sciences, 2020
In order to quantitatively describe the time-varying mechanical properties of asphalt mixture during creep process, a nonlinear viscoelastoplastic creep model was proposed, by using variable-order fractional calculus.
Wenbo Luo, Bo Li, Yongjun Zhang, Boyuan Yin, Jingling Dai   +4 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Finite Element Solutions for the Space Fractional Diffusion Equation with a Nonlinear Source Term

Abstract and Applied Analysis, 2012
We consider finite element Galerkin solutions for the space fractional diffusion equation with a nonlinear source term. Existence, stability, and order of convergence of approximate solutions for the backward Euler fully discrete scheme have been ...
Y. J. Choi, S. K. Chung
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source