Results 61 to 70 of about 47,117 (300)

High-Resolution Diffusion Tensor Spinal Cord MRI Measures as Biomarkers of Disability Progression in a Rodent Model of Progressive Multiple Sclerosis. [PDF]

PLoS ONE, 2016
Disease in the spinal cord is a major component of disability in multiple sclerosis, yet current techniques of imaging spinal cord injury are insensitive and nonspecific.
Francesca Gilli, Xi Chen, Andrew R Pachner, Barjor Gimi   +3 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Stability effects on results of diffusion tensor imaging analysis by reduction of the number of gradient directions due to motion artifacts: an application to presymptomatic Huntington's disease. [PDF]

, 2011
In diffusion tensor imaging (DTI), an improvement in the signal-to-noise ratio (SNR) of the fractional anisotropy (FA) maps can be obtained when the number of recorded gradient directions (GD) is increased.
Müller, HP, Kassubek, J, Landwehrmeyer, GB, Kloppel, S, Tabrizi, SJ, Süssmuth, SD, Ludolph, A   +6 more
core  

1000-subject high-resolution fractional anisotropy template [PDF]

Fractional anisotropy template in MNI 2009b NLIN Asymmetric space (0.5 mm resolution).
Andreas Horn (7066955), Gavin Elias (17016891), Ningfei Li (17016894)   +2 more
core   +1 more source

Correlation of dMRI fractional anisotropy with clinical measures of glaucoma (n = 6). [PDF]

, 2019
(A) Vertical cup-to-disc ratio predicts optic nerve fractional anisotropy (p = 0.0077, R2 = 0.66). (B) Average retinal nerve fiber layer thickness predicts optic nerve fractional anisotropy (p = 0.0069, R2 = 0.63).
Yao Liu (173014), Bas Rokers (839541), Nathaniel Miller (6785780), Roman Krivochenitser (6785783)   +3 more
core   +1 more source

White matter integrity of substance and behavioral addiction: A Fractional anisotropy meta-analysis [PDF]

, 2023
This is a quantitative Fractional anisotropy meta-analysis of substance and behavioral ...
Yang Zhenzhen, Benjamin Klugah-Brown, Ding Guobin   +2 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Microscopic diffusion anisotropy in the human brain: Reproducibility, normal values, and comparison with the fractional anisotropy

NeuroImage, 2015
Human neuroimaging of tissue microstructure, such as axonal density and integrity, is key in clinical and neuroscience research. Most studies rely on diffusion tensor imaging (DTI) and the measures derived from it, most prominently fractional anisotropy (FA). However, FA also depends on fiber orientation distribution, a more macroscopic tissue property.
Marco Lawrenz, Stefanie Brassen, Jürgen Finsterbusch   +2 more
openaire   +2 more sources

Histograms of fractional anisotropy in pure white matter at age 9 and age 12. [PDF]

, 2012
In the 14 children with relatively large volumetric white matter growth mean fractional anisotropy was 0.43 at both ages. In 13 children with relatively small volumetric white matter growth, mean fractional anisotropy increased from 0.41 to 0.44.
Hugo G. Schnack (169589), René S. Kahn (91645), Dorret I. Boomsma (109746), Jiska S. Peper (171256), H. E. Hulshoff Pol (171262), Rachel M. Brouwer (169603), G. Caroline van Baal (171254), Inge L. C. van Soelen (171251), René C. W. Mandl (171245)   +8 more
core   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source