Results 61 to 70 of about 460,716 (260)

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Early-stage psychotherapy produces elevated frontal white matter integrity in adult major depressive disorder.

PLoS ONE, 2013
BackgroundPsychotherapy has demonstrated comparable efficacy to antidepressant medication in the treatment of major depressive disorder. Metabolic alterations in the MDD state and in response to treatment have been detected by functional imaging methods,
Tao Wang, Xiaolan Huang, Peiyu Huang, Dan Li, Fajin Lv, Yong Zhang, Linke Zhou, Deyu Yang, Peng Xie   +8 more
doaj   +1 more source

Correlation between white matter damage and gray matter lesions in multiple sclerosis patients

Neural Regeneration Research, 2017
We observed the characteristics of white matter fibers and gray matter in multiple sclerosis patients, to identify changes in diffusion tensor imaging fractional anisotropy values following white matter fiber injury.
Xue-mei Han, Hong-ji Tian, Zheng Han, Ce Zhang, Ying Liu, Jie-bing Gu, Rohit Bakshi, Xia Cao   +7 more
doaj   +1 more source

Aortic Stiffness and White Matter Microstructural Integrity Assessed by Diffusion Tensor Imaging: The ARIC‐NCS

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Changes in white matter microstructural integrity are detectable before appearance of white matter lesions on magnetic resonance imaging as a manifestation of cerebral small‐vessel disease.
Jingkai Wei, Priya Palta, Michelle L. Meyer, Anna Kucharska‐Newton, Brian W. Pence, Allison E. Aiello, Melinda C. Power, Keenan A. Walker, A. Richey Sharrett, Hirofumi Tanaka, Clifford R. Jack, Thomas H. Mosley, Robert I. Reid, Denise A. Reyes, Gerardo Heiss   +14 more
doaj   +1 more source

The value of quantitative diffusion tensor imaging indices of spinal cord disorders

The Egyptian Journal of Radiology and Nuclear Medicine, 2021
Background Different lesions affecting the spinal cord can lead to myelopathy. Diffusion tensor imaging (DTI) is widely used to predict the degree of spinal cord microstructure affection and to assess axonal integrity and diffusion directionality.
Mohammad Koriem Mahmoud Omar, Abd El-Karem Hasan Abd Allah, Mona Gouda Maghrabi, Mohamed Zidan Mohamed   +3 more
doaj   +1 more source

Cognitive Deficits, Apathy, and Hypersomnolence Represent the Core Brain Symptoms of Adult-Onset Myotonic Dystrophy Type 1

Frontiers in Neurology, 2021
Myotonic dystrophy type 1 is the most common form of muscular dystrophy in adults, and is primarily characterized by muscle weakness and myotonia, yet some of the most disabling symptoms of the disease are cognitive and behavioral.
Jacob N. Miller, Alison Kruger, David J. Moser, Laurie Gutmann, Ellen van der Plas, Timothy R. Koscik, Sarah A. Cumming, Darren G. Monckton, Peggy C. Nopoulos, Peggy C. Nopoulos, Peggy C. Nopoulos   +10 more
doaj   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Multi-Shell Hybrid Diffusion Imaging (HYDI) at 7 Tesla in TgF344-AD Transgenic Alzheimer Rats. [PDF]

PLoS ONE, 2015
Diffusion weighted imaging (DWI) is widely used to study microstructural characteristics of the brain. Diffusion tensor imaging (DTI) and high-angular resolution imaging (HARDI) are frequently used in radiology and neuroscience research but can be ...
Madelaine Daianu, Russell E Jacobs, Tara M Weitz, Terrence C Town, Paul M Thompson   +4 more
doaj   +1 more source

Optic nerve fractional anisotropy ratios in glaucoma patients (n = 6) and controls (n = 6).

, 2019
Comparison of optic nerve fractional anisotropy ratios (%) in glaucoma patients (green) and controls (blue). Glaucoma patient ratios were calculated for “advanced” / “mild” optic nerve fractional anisotropy, and control subject ratios were calculated for
Yao Liu (173014), Bas Rokers (839541), Nathaniel Miller (6785780), Roman Krivochenitser (6785783)   +3 more
core   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source