Results 61 to 70 of about 46,949 (300)

Cognitive Deficits, Apathy, and Hypersomnolence Represent the Core Brain Symptoms of Adult-Onset Myotonic Dystrophy Type 1

Frontiers in Neurology, 2021
Myotonic dystrophy type 1 is the most common form of muscular dystrophy in adults, and is primarily characterized by muscle weakness and myotonia, yet some of the most disabling symptoms of the disease are cognitive and behavioral.
Jacob N. Miller, Alison Kruger, David J. Moser, Laurie Gutmann, Ellen van der Plas, Timothy R. Koscik, Sarah A. Cumming, Darren G. Monckton, Peggy C. Nopoulos, Peggy C. Nopoulos, Peggy C. Nopoulos   +10 more
doaj   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Gray and White Matter Contributions to Cognitive Frontostriatal Deficits in Non-Demented Parkinson's Disease.

PLoS ONE, 2016
ObjectiveThis prospective investigation examined: 1) processing speed and working memory relative to other cognitive domains in non-demented medically managed idiopathic Parkinson's disease, and 2) the predictive role of cortical/subcortical gray ...
Catherine C Price, Jared Tanner, Peter T Nguyen, Nadine A Schwab, Sandra Mitchell, Elizabeth Slonena, Babette Brumback, Michael S Okun, Thomas H Mareci, Dawn Bowers   +9 more
doaj   +1 more source

Correlation between white matter damage and gray matter lesions in multiple sclerosis patients

Neural Regeneration Research, 2017
We observed the characteristics of white matter fibers and gray matter in multiple sclerosis patients, to identify changes in diffusion tensor imaging fractional anisotropy values following white matter fiber injury.
Xue-mei Han, Hong-ji Tian, Zheng Han, Ce Zhang, Ying Liu, Jie-bing Gu, Rohit Bakshi, Xia Cao   +7 more
doaj   +1 more source

Aortic Stiffness and White Matter Microstructural Integrity Assessed by Diffusion Tensor Imaging: The ARIC‐NCS

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Changes in white matter microstructural integrity are detectable before appearance of white matter lesions on magnetic resonance imaging as a manifestation of cerebral small‐vessel disease.
Jingkai Wei, Priya Palta, Michelle L. Meyer, Anna Kucharska‐Newton, Brian W. Pence, Allison E. Aiello, Melinda C. Power, Keenan A. Walker, A. Richey Sharrett, Hirofumi Tanaka, Clifford R. Jack, Thomas H. Mosley, Robert I. Reid, Denise A. Reyes, Gerardo Heiss   +14 more
doaj   +1 more source

Additive Gaussian Process Regression for Predictive Design of High‐Performance, Printable Silicones

Advanced Engineering Materials, EarlyView.
A chemistry‐aware design framework for tuning printable polydimethylsiloxane (PDMS) for vat photopolymerization (VPP) is developed using additive Gaussian process (GP) modeling. Polymer network mechanics informs variable groupings, feasible formulation constraints, and interaction variables.
Roxana Carbonell, Martha Leach, Hongtao Song, Carolyn Seepersad   +3 more
wiley   +1 more source

Mean fractional anisotropy map from 21 chimpanzees.

, 2013
Mean fractional anisotropy map from 21 chimpanzees.
Kimberley A. Phillips (332996), William D. Hopkins (49851)   +1 more
core   +1 more source

Thermodynamic Pathways of Nonequilibrium Solidification in Wire‐Arc Additive Manufacturing Fe‐Based Multicomponent Alloy Structures

Advanced Engineering Materials, EarlyView.
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios, Anthony Gonzalez, Aleksander Aleman, Tyler Dolmetsch, Tanaji Paul, Arvind Agarwal   +5 more
wiley   +1 more source

Impact of the control for corrupted diffusion tensor imaging data in comparisons at the group level : an application in Huntington disease

, 2014
This work was supported by the European Union under the Seventh Framework programme– PADDINGTON Project, Grant Agreement No. 261358, and the European Huntington’s Disease Network (EHDN), project 070 – PADDINGTON.Background: Corrupted gradient directions (
Landwehrmeyer, G.B., Muller, H.P., Müller, H.-P., Hobbs, N.Z., Kassubek, J., Orth, M., Tabrizi, S.J., Klöppel, S., Sprengelmeyer, R., Ludolph, A.C., Süssmuth, S.D., Grön, G., Duerr, A., Roos, R.A.C.   +13 more
core   +1 more source

Early-stage psychotherapy produces elevated frontal white matter integrity in adult major depressive disorder.

PLoS ONE, 2013
BackgroundPsychotherapy has demonstrated comparable efficacy to antidepressant medication in the treatment of major depressive disorder. Metabolic alterations in the MDD state and in response to treatment have been detected by functional imaging methods,
Tao Wang, Xiaolan Huang, Peiyu Huang, Dan Li, Fajin Lv, Yong Zhang, Linke Zhou, Deyu Yang, Peng Xie   +8 more
doaj   +1 more source