Results 71 to 80 of about 53,428 (260)
Optimal Random Search, Fractional Dynamics and Fractional Calculus [PDF]
Volume 4: 18th Design for Manufacturing and the Life Cycle Conference; 2013 ASME/IEEE International Conference on Mechatronic and Embedded Systems and Applications, 2013 What is the most efficient search strategy for the random located target sites subject to the physical and biological constraints? Previous results suggested the Levy flight is the best option to characterize this optimal problem, however, which ignores the understanding and learning abilities of the searcher agents.
Zeng, Caibin, Chen, Yangquan
openaire +3 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Analogue Realization of Fractional-Order Dynamical Systems
Entropy, 2013 As it results from many research works, the majority of real dynamical objects are fractional-order systems, although in some types of systems the order is very close to integer order.
Ladislav Pivka +5 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
A dynamic programming approach to adaptive fractionation [PDF]
Physics in Medicine and Biology, 2012 We conduct a theoretical study of various solution methods for the adaptive fractionation problem. The two messages of this paper are: (i) dynamic programming (DP) is a useful framework for adaptive radiation therapy, particularly adaptive fractionation, because it allows us to assess how close to optimal different methods are, and (ii) heuristic ...
Ramakrishnan, Jagdish +3 more
openaire +5 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The Impact of Memory Effects on Lymphatic Filariasis Transmission Using Incidence Data From Ghana
Engineering ReportsLymphatic filariasis is a neglected tropical disease caused by a parasitic worm transmitted to humans by a mosquito bite. In this study, a mathematical model is developed using the Caputo fractional operator.
Fredrick A. Wireko +5 more
doaj +1 more source
Memory-Dependent Dynamics of Trachoma with Real Data Analysis from Cameroon via Fractional Framework
Fractal and FractionalThis study models trachoma transmission in Cameroon using a deterministic approach with integer and fractional-order derivatives, incorporating direct, fly-mediated, and environmental transmission routes.
Ardo Sylvain Gouroudja Banbeto +5 more
doaj +1 more source