Results 81 to 90 of about 18,801 (261)

Sargassum Lung Syndrome: Air Flow Obstruction and Bronchial Inflammation Are Observed After Prolonged Exposure to Sargassum Gas Emissions in the Eastern Caribbean

Environmental Toxicology, EarlyView.
ABSTRACT Sargassum inundation of Caribbean and American shorelines is a growing environmental hazard. Hydrogen sulfide (H2S) and ammonia (NH3) produced by decomposing Sargassum could be involved in airway obstruction and bronchial inflammation. The study was undertaken to evaluate the effects of exposure to H2S and NH3 gases emitted during Sargassum ...
Rishika Banydeen, Jonathan Florentin, Maxime Boutourlinsky, Remi Nguyen, Fatima Radouani, Moustapha Agossou, Gary Lutin, Thierry Lebrun, Remi Neviere, Dabor Resiere   +9 more
wiley   +1 more source

Clinical utility of fractional exhaled nitric oxide in severe asthma management

European Respiratory Journal, 2020
Asthma is a chronic inflammatory disease of the airways, affecting over 350 million people worldwide and placing a significant burden on healthcare providers and wider society.
A. Menzies-Gow, A. Mansur, C. Brightling
semanticscholar   +1 more source

Small Airways Dysfunction and Remission in Adults With Asthma: A Longitudinal Exploratory Analysis of the AssessmenT of smalL Airways involvemeNT In aSthma (ATLANTIS) Study

Allergy, EarlyView.
We conducted a post hoc analysis of ATLANTIS, a multinational prospective study including 684 adults with asthma. Fewer small airway symptoms and lower disease activity are independently associated with asthma remission. Replicated airway transcriptomic signatures show increased IL‐4/13 signalling and reduced coagulation pathways across the ATLANTIS ...
Akshi Kumar, Rory Chan, Nazanin Zounemat‐Kermani, Eleanor Quek, Ian M. Adcock, Bianca Beghe, Christopher Brightling, Dave Singh, Janwillem Kocks, Alberto Papi, Klaus F. Rabe, Ulrica Scaffidi‐Argentina, Maarten van den Berge, Monica Kraft, Salman Siddiqui   +14 more
wiley   +1 more source

Effects of Exposure to New Car Interiors in Patients With Asthma and Allergic Rhinitis

Allergy & Rhinology, 2018
Rationale Vehicle interiors are an important microenvironment for atopic subjects. This study evaluated the subjective and objective physiologic and clinical effects of exposing subjects with asthma and allergic rhinitis to new 2017 Mercedes vehicles ...
Amber N. Pepper MD, Adeeb Bulkhi MD, MS, Catherine R. Smith CMA, CCRC, Matthias Colli, Karl-Christian Bergmann MD, Torsten Zuberbier MD, PhD, Thomas B. Casale MD   +6 more
doaj   +1 more source

Exhaled Volatile Organic Compounds Identify Allergic Patients Among Individuals With Chronic Rhinitis

Allergy, EarlyView.
Exhaled decane and nonadecane discriminate allergic (AR + LAR) from non‐allergic (NAR + HC) subjects among individuals with chronic rhinitis. LAR patients display higher levels of exhaled nonadecane than NAR individuals at baseline. Subjects with FeNO≥ 25 ppb have higher levels of exhaled decane, nonanal, and styrene than individuals with FeNO < 25 ppb
Rosa Alba Sola‐Martinez, Laura Zubiaga‐Fernandez, Marta Figuerola, Anyith Cruz‐Amaya, Carlos J. Aranda, Maria J. Torres, Ibon Eguiluz‐Gracia, Carmen Rondon, Teresa De Diego Puente, Almudena Testera‐Montes   +9 more
wiley   +1 more source

Data on the oral CRTh2 antagonist QAW039 (fevipiprant) in patients with uncontrolled allergic asthma

Data in Brief, 2016
This article contains data on clinical endpoints (Peak Flow Expiratory Rate, fractional exhaled nitric oxide and total IgE serum levels) and plasma pharmacokinetic parameters concerning the use of the oral CRTh2 antagonist QAW039 (fevipiprant) in mild to
Veit J. Erpenbeck, Todor A. Popov, David Miller, Steven F. Weinstein, Sheldon Spector, Baldur Magnusson, Wande Osuntokun, Paul Goldsmith, Markus Weiss, Jutta Beier   +9 more
doaj   +1 more source

Nasal Airway Transcriptome Reflects Selected Asthma‐Associated Gene Signatures in the Lower Airways

Allergy, EarlyView.
Seven genes and two gene modules were consistently associated with asthma in both airway compartments in ARMS and were validated in ATLANTIS. The two modules reflected IL‐13 related inflammation and mast cell activity, respectively. Nasal gene signatures provide a non‐invasive proxy for selected bronchial asthma‐associated gene signatures. ARMS, Asthma
Hui Wen, Tessa Kole, Orestes A. Carpaij, Tatiana Karp, Victor Guryev, Alen Faiz, Kian Fan Chung, Pankaj Bhavsar, Ian M. Adcock, Salman Siddiqui, Andy Lan, Katie L. Raby, Nazanin Zounemat‐Kermani, Chris Brightling, Dave Singh, Janwillem Kocks, Monica Kraft, Bianca Beghé, Klaus F. Rabe, Alberto Papi, Machteld N. Hylkema, Martijn C. Nawijn, Maarten van den Berge   +22 more
wiley   +1 more source

Measurement of Fractional Exhaled Nitric Oxide with a Stationary Analyzer（NOA280i®）or Hand-held Analyzer（NIOX MINO®）Shows a Strong Correlation but Weaker Correlation at Higher Levels [PDF]

, 2019
This study investigated the difference of measured values between two types of analyzer over a wider range of fractional exhaled nitric oxide （FeNO） levels than in previous reports because some asthma patients have high FeNO levels.
Shimizu, Yasuo, Shimizu, Yuka, Morita, Hiroko, Ito, Hiroshi, Chibana, Kazuyuki, Okutomi, Tomoko, Takemasa, Akihiro, Miyoshi, Masaaki, Arai, Ryo, Masawa, Meitetsu, Nakamura, Yusuke, Okutomi, Hiroaki, Yokoyama, Tatsuya, Koike, Ryosuke, Uchida, Nobuhiko, Soda, Sayo, Ikeda, Naoya, Shiobara, Taichi, Watanabe, Taiji   +18 more
core  

Application of whole exome sequencing in patients with primary ciliary dyskinesia

Zhongguo Linchuang Yixue
A 29-year-old man visited Zhongshan Hospital, Fudan University in December 2021. The patient presented with recurrent coughing, sputum, and wheezing, high level of serum total IgE, positive aspergillus fumigatus-specific IgE and extremely severe mixed ...
Ke CHEN, Jing SHI, Lijuan HU, Li ZHANG, Minlu CAO, Wei GUO, Meiling JIN   +6 more
doaj   +1 more source

Fractional Exhaled Nitric Oxide in Healthy Tibetans at High Altitude [PDF]

Medical Science Monitor, 2014
Fractional exhaled NO (FENO) is a marker of airway inflammation. For successful use of this marker it is important to have reference ranges from different healthy populations. The aim of this study was to establish these in healthy Tibetan adults who had always lived at high altitude on the Qinghai-Tibet Plateau.The study included 145 healthy Tibetan ...
Ren, Xuewen, Wang, Hao, Hong, Heng, Qiao, Huaiyu, Man, Chunyan, Zhao, Gang, Chen, Li, Li, Tanshi   +7 more
openaire   +2 more sources