Results 71 to 80 of about 251,245 (326)

Multiparametric Cardiac 18F-FDG PET: Pilot Comparison of FDG Delivery Rate with 82Rb Myocardial Blood Flow [PDF]

open access: yes, 2020
Myocardial blood flow (MBF) and flow reserve are usually quantified in the clinic with positron emission tomography (PET) using a perfusion-specific radiotracer (e.g. 82Rbchloride). However, the clinical accessibility of existing perfusion tracers remains limited.
arxiv   +1 more source

Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization [PDF]

open access: yes, 2016
Objectives The aim of this study was to compare microvascular resistance under both baseline and hyperemic conditions immediately after percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) with an unobstructed reference vessel in ...
Alamgir, Farquad   +5 more
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Role of measurement of fractional flow reserve in coronary artery atherosclerosis

open access: yesТерапевтический архив, 2015
The paper considers coronary flow in health and coronary flow autoregulation in health and disease. It gives basic methods used to estimate coronary flow reserve in patients with coronary atherosclerosis.
F Yu Kopylov   +3 more
doaj  

Deep Learning-Based Prediction of Fractional Flow Reserve along the Coronary Artery [PDF]

open access: yesarXiv, 2023
Functionally significant coronary artery disease (CAD) is caused by plaque buildup in the coronary arteries, potentially leading to narrowing of the arterial lumen, i.e. coronary stenosis, that significantly obstructs blood flow to the myocardium. The current reference for establishing the presence of a functionally significant stenosis is invasive ...
arxiv  

Stability of Diluted Adenosine Solutions in Polyolefin Infusion Bags [PDF]

open access: yes, 2013
Background Intravenous or intracoronary adenosine is used in the cardiac catherization lab to achieve maximal coronary blood flow and determine fractional flow reserve.
Almagambetova, Elise   +3 more
core   +2 more sources

Fractional flow reserve in patients with reduced ejection fraction

open access: yesEuropean Heart Journal, 2019
Abstract Aims Fractional flow reserve (FFR) has never been investigated in patients with reduced ejection fraction and associated coronary artery disease (CAD). We evaluated the impact of FFR on the management strategies of these patients and related outcomes.
Giuseppe Di Gioia   +18 more
openaire   +4 more sources

End-Diastolic Fractional Flow Reserve [PDF]

open access: yesCirculation: Cardiovascular Interventions, 2014
Background— Diastolic fractional flow reserve (dFFR) has been shown to be highly sensitive for detection of inducible myocardial ischemia. However, its reliance on measurement of left-ventricular pressure for zero-flow pressure correction, as well as manual extraction of the diastolic interval, has been its major limitation ...
David A. Chalyan   +3 more
openaire   +3 more sources

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

open access: yesFEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada   +3 more
wiley   +1 more source

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