Results 81 to 90 of about 111,080 (399)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Stability of Diluted Adenosine Solutions in Polyolefin Infusion Bags [PDF]

, 2013
Background Intravenous or intracoronary adenosine is used in the cardiac catherization lab to achieve maximal coronary blood flow and determine fractional flow reserve.
Almagambetova, Elise, Blais, Danielle M., Hutchinson, David, Zhao, Fang   +3 more
core   +2 more sources

Relationship Between Endothelial Wall Shear Stress and High‐Risk Atherosclerotic Plaque Characteristics for Identification of Coronary Lesions That Cause Ischemia: A Direct Comparison With Fractional Flow Reserve

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background Wall shear stress (WSS) is an established predictor of coronary atherosclerosis progression. Prior studies have reported that high WSS has been associated with high‐risk atherosclerotic plaque characteristics (APCs).
Donghee Han, Anna Starikov, Bríain ó Hartaigh, Heidi Gransar, Kranthi K. Kolli, Ji Hyun Lee, Asim Rizvi, Lohendran Baskaran, Joshua Schulman‐Marcus, Fay Y. Lin, James K. Min   +10 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Lesion-Specific Peri-Coronary Fat Attenuation Index Is Associated With Functional Myocardial Ischemia Defined by Abnormal Fractional Flow Reserve

Frontiers in Cardiovascular Medicine, 2021
Background: The association between abnormal invasive fractional flow reserve (FFR) and the fat attenuation index (FAI) of lesion-specific peri-coronary adipose tissue (PCAT) is unclear. Method: Data of patients who underwent coronary computed tomography
Shaowei Ma, Xujiao Chen, Yue Ma, Hui Liu, Jiayin Zhang, Lei Xu, Yining Wang, Ting Liu, Kunhua Wang, Jinzhu Yang, Yang Hou   +10 more
semanticscholar   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

cFFR as an alternative to FFR: please do not contrast simplicity! [PDF]

, 2017
info:eu-repo/semantics ...
Amabile, N, Baptista, SB, Cialdella, P, Leone, AM, Martin-Reyes, R, Raposo, L   +5 more
core   +1 more source

Role of measurement of fractional flow reserve in coronary artery atherosclerosis

Терапевтический архив, 2015
The paper considers coronary flow in health and coronary flow autoregulation in health and disease. It gives basic methods used to estimate coronary flow reserve in patients with coronary atherosclerosis.
F Yu Kopylov, A A Bykova, Yu V Vasilevsky, S S Simakov   +3 more
doaj  

Fractional flow reserve in patients with reduced ejection fraction

European Heart Journal, 2019
Abstract Aims Fractional flow reserve (FFR) has never been investigated in patients with reduced ejection fraction and associated coronary artery disease (CAD). We evaluated the impact of FFR on the management strategies of these patients and related outcomes.
Giuseppe Di Gioia, Bernard De Bruyne, Mariano Pellicano, Jozef Bartunek, Iginio Colaiori, Antonella Fiordelisi, Grazia Canciello, Panagiotis Xaplanteris, Stephane Fournier, Asim Katbeh, Danilo Franco, Monika Kodeboina, Carmine Morisco, Frank Van Praet, Filip Casselman, Ivan Degrieck, Bernard Stockman, Marc Vanderheyden, Emanuele Barbato   +18 more
openaire   +4 more sources

Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease.

New England Journal of Medicine, 2019
BACKGROUND In patients with stable angina, two strategies are often used to guide revascularization: one involves myocardial-perfusion cardiovascular magnetic resonance imaging (MRI), and the other involves invasive angiography and measurement of ...
E. Nagel, J. Greenwood, G. Mccann, N. Bettencourt, A. Shah, Shazia T. Hussain, D. Perera, S. Plein, C. Bucciarelli-Ducci, Matthias Paul, M. Westwood, M. Marber, W. Richter, V. Puntmann, C. Schwenke, J. Schulz-Menger, R. Das, J. Wong, D. Hausenloy, H. Steen, C. Berry   +20 more
semanticscholar   +1 more source