Results 101 to 110 of about 234,622 (320)
Some results on quantum Hahn integral inequalities
Journal of Inequalities and Applications, 2019 In this paper the quantum Hahn difference operator and the quantum Hahn integral operator are defined via the quantum shift operator Φqθ(t)=qt+(1−q)θ $_{\theta }\varPhi _{q}(t)=qt+(1-q)\theta $, t∈[a,b] $t\in [a,b]$, θ=ω/(1−q)+a $\theta = \omega /(1-q)+a$
Suphawat Asawasamrit +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Weak Type Inequalities for Some Integral Operators on Generalized Nonhomogeneous Morrey Spaces
Journal of Function Spaces and Applications, 2013 We prove weak type inequalities for some integral operators, especially generalized fractional integral operators, on generalized Morrey spaces of nonhomogeneous type.
Hendra Gunawan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Extremal solutions of $ \varphi- $Caputo fractional evolution equations involving integral kernels
, 2021 Apassara Suechoei +1 more
openalex +1 more source
The monotone iterative method for the integral boundary value problems of fractionalp-Laplacian equations with delay [PDF]
, 2020 Chunyan Wei +3 more
openalex +1 more source
Some Integral Inequalities for Local Fractional Integrals
International Journal of Analysis and Applications, 2017 In this paper, firstly we extend some generalization of the Hermite-Hadamard inequality and Bullen inequality to generalized convex functions. Then, we give some important integral inequalities related to these inequalities.
Sarikayala, M. Zeki +2 more
openaire +5 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source