Results 111 to 120 of about 33,681 (303)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Some new inequalities for generalized fractional conformable integral operators

Advances in Difference Equations, 2019
The present paper aims to establish certain new classes of integral inequalities for a class of n ( n∈N $n\in \mathbb{N}$) positive continuous and decreasing functions by utilizing the generalized fractional conformable integral operators (FCIO) recently
Kottakkaran Sooppy Nisar, Gauhar Rahman, Aftab Khan   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Fractional Integral Inequalities of Gruss Type via Generalized Mittag-Leffler Function

International Journal of Analysis and Applications, 2019
We use generalized fractional integral operator containing the generalized Mittag-Leffler function to establish some new integral inequalities of Gr¨uss type. A cluster of fractional integral inequalities have been identified by setting particular values
G. Farid, A. U. Rehman, Vishnu Narayan Mishra, S. Mehmood   +3 more
doaj   +2 more sources

Weak Type Inequalities for Some Integral Operators on Generalized Nonhomogeneous Morrey Spaces

Journal of Function Spaces and Applications, 2013
We prove weak type inequalities for some integral operators, especially generalized fractional integral operators, on generalized Morrey spaces of nonhomogeneous type.
Hendra Gunawan, Denny Ivanal Hakim, Yoshihiro Sawano, Idha Sihwaningrum   +3 more
doaj   +1 more source

Fractional integrals of generalized functions [PDF]

Journal of the Australian Mathematical Society, 1972
The concept of integrals of fractional order of a function f, defined by if Reα > 0, can be extended to generalised functions in the framework of the theory of convolution of distributions. The resulting theory [2, Chap. I §5.5] is very satisfactory for many purposes but there are circumstances in which it is not suitable.
openaire   +2 more sources

Pricing European and Barrier Options in the Fractional Black-Scholes Market [PDF]

The aim of this paper is to obtain the valuation formulas for European and barrier options if the underlying of the option contract is supposed to be driven by a fractional Brownian motion with Hurst parameter greater than 0.5.
Ciprian Necula
core  

Control strategy for anaesthetic drug dosage with interaction among human physiological organs using optimal fractional order PID controller

, 2014
In this paper, an efficient control strategy for physiological interaction based anaesthetic drug infusion model is explored using the fractional order (FO) proportional integral derivative (PID) controllers.
Koushik Maharatna, Das, Saptarshi, Sourav Das, Saptarshi Das, Das, Sourav, Maharatna, Koushik   +5 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source