Results 101 to 110 of about 33,681 (303)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Advances in Difference Equations, 2020 The present work investigates the applicability and effectiveness of generalized proportional fractional integral ( GPFI $\mathcal{GPFI}$ ) operator in another sense.
Thabet Abdeljawad +4 more
doaj +1 more source
ON REFINEMENTS of HERMITE–HADAMARD TYPE INEQUALITIES with GENERALIZED FRACTIONAL INTEGRAL OPERATORS
, 2021 In this paper we establish the refinements of Hermite-Hadamard type inequalities for generalized fractional integral operator through the instrument of convex functions. © 2021 Asian Journal of Dairy and Food Research.
Hüseyin Budak +4 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Certain Inequalities Involving Generalized Erdélyi-Kober Fractional q-Integral Operators
The Scientific World Journal, 2014 In recent years, a remarkably large number of inequalities involving the fractional q-integral operators have been investigated in the literature by many authors.
Praveen Agarwal +3 more
doaj +1 more source
Some results on quantum Hahn integral inequalities
Journal of Inequalities and Applications, 2019 In this paper the quantum Hahn difference operator and the quantum Hahn integral operator are defined via the quantum shift operator Φqθ(t)=qt+(1−q)θ $_{\theta }\varPhi _{q}(t)=qt+(1-q)\theta $, t∈[a,b] $t\in [a,b]$, θ=ω/(1−q)+a $\theta = \omega /(1-q)+a$
Suphawat Asawasamrit +3 more
doaj +1 more source
Fractional variational problems with the Riesz-Caputo derivative
, 2012 In this paper we investigate optimality conditions for fractional variational problems, with a Lagrangian depending on the Riesz-Caputo derivative. First we prove a generalized Euler-Lagrange equation for the case when the interval of integration of the ...
Almeida, R. +2 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
On applications of Caputo k-fractional derivatives
Advances in Difference Equations, 2019 This research explores Caputo k-fractional integral inequalities for functions whose nth order derivatives are absolutely continuous and possess Grüss type variable bounds. Using Chebyshev inequality (Waheed et al. in IEEE Access 7:32137–32145, 2019) for
Ghulam Farid +5 more
doaj +1 more source