Generalizations of some fractional integral inequalities via generalized Mittag-Leffler function. [PDF]
J Inequal Appl, 2017 Abbas G, Khan KA, Farid G, Rehman AU.
europepmc +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Grüss-type inequalities involving functional bounds via analytic kernel fractional integral. [PDF]
MethodsXNeamah MK +3 more
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Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
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Some new applications of the fractional integral and four-parameter Mittag-Leffler function. [PDF]
PLoS OneAbubaker AA +3 more
europepmc +1 more source
Some new k-Riemann-Liouville fractional integral inequalities associated with the strongly η-quasiconvex functions with modulus μ≥0. [PDF]
J Inequal Appl, 2018 Nwaeze ER, Kermausuor S, Tameru AM.
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Advancements in integral inequalities of Ostrowski type via modified Atangana-Baleanu fractional integral operator. [PDF]
HeliyonRahman G +4 more
europepmc +1 more source
Weighted inequalities for fractional integral operators and linear commutators in the Morrey-type spaces. [PDF]
J Inequal Appl, 2017 Wang H.
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