Results 51 to 60 of about 84,165 (291)

Optimality and duality results for E-differentiable multiobjective fractional programming problems under E-convexity

Journal of Inequalities and Applications, 2019
A new class of (not necessarily differentiable) multiobjective fractional programming problems with E-differentiable functions is considered. The so-called parametric E-Karush–Kuhn–Tucker necessary optimality conditions and, under E-convexity hypotheses,
Tadeusz Antczak, Najeeb Abdulaleem
doaj   +1 more source

An SDP Approach For Solving Quadratic Fractional Programming Problems [PDF]

, 2014
This paper considers a fractional programming problem (P) which minimizes a ratio of quadratic functions subject to a two-sided quadratic constraint. As is well-known, the fractional objective function can be replaced by a parametric family of quadratic ...
Nguyen, Van-Bong, Sheu, Ruey-Lin, Xia, Yong   +2 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Generalized Heptagonal Membership Function for Fully Fuzzy Linear Fractional Programming Problems

Ibn Al-Haitham Journal for Pure and Applied Sciences
    Identifying the optimum solution that satisfies the restrictions and maximizes or minimizes the objective function is the aim of fully fuzzy fractional programming (FFFLP). Due to the inclusion of both fuzzy parameters and fractional variables, this
Israa Hadi, Iden H. Al Kanani
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Program Fraksional Linier Dengan Koefisien Interval [PDF]

, 2014
Linear fractional programming is a special case of nonlinear programming which the objective function is a ratio of two linear function with linear constraints.
Sari, A. R. (Annisa), Sunarsih, S. (Sunarsih), Suryoto, S. (Suryoto)   +2 more
core  

Fractional Order Version of the HJB Equation

, 2018
We consider an extension of the well-known Hamilton-Jacobi-Bellman (HJB) equation for fractional order dynamical systems in which a generalized performance index is considered for the related optimal control problem.
AsadiZadehShiraz, Mehdi, Razminia, Abolhassan, Torres, Delfim F. M.   +2 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

An Algorithm for Quadratically Constrained Multi-objective Quadratic Fractional Programming with Pentagonal Fuzzy Numbers [PDF]

Operations Research and Decisions, 2022
This study proposes a methodology to obtain an efficient solution for a programming model which is multi-objective quadratic fractional with pentagonal fuzzy numbers as coefficients in all the objective functions and constraints.
Vandana Goyal, Namrata Rani, Deepak Gupta   +2 more
doaj