Results 251 to 260 of about 5,538,805 (353)

Alterations of Amino Acids and Monoamine Metabolism inMale Fmr1 Knockout Mice: A Putative Animal Model ofthe Human Fragile X Mental Retardation Syndrome [PDF]

, 2001
Michael Gruß, Katharina Braun
openalex   +1 more source

Sustained Epigenetic Reactivation in Fragile X Neurons with an RNA-Binding Small Molecule. [PDF]

Genes (Basel)
Kam CW, Dumelie JG, Ciceri G, Yang WY, Disney MD, Studer L, Jaffrey SR.   +6 more
europepmc   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

Advanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie, Meng Pan, Zeyuan Zhang, Licheng Zhang, Haotian Liu, Xia Wang, William W Lu, Peifu Tang, Wei Ge   +8 more
wiley   +1 more source

Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neurons

Proceedings of the National Academy of Sciences of the United States of America, 2016
Ricardos Tabet, Enora Moutin, J. Becker, D. Heintz, Laetitia Fouillen, E. Flatter, W. Krężel, Violaine Alunni, P. Koebel, D. Dembélé, F. Tassone, B. Bardoni, J. Mandel, N. Vitale, D. Muller, J. Le Merrer, H. Moine   +16 more
semanticscholar   +1 more source

Targeting GABA Polarity During Cortical Development Improves Circuit and Sensory Deficits in Fragile X Mice. [PDF]

Biol Psychiatry
Padmashri R, Dunaevsky A.
europepmc   +1 more source

The Molecular Basis of Amino Acids Sensing

Advanced Science, EarlyView.
Amino acids are essential as protein building blocks and signaling molecules, enabling metabolic regulation. Cells sense amino acid levels to control protein synthesis, maintain homeostasis, and adapt to nutritional changes. This review explores recent advances in amino acid sensing mechanisms across organisms, highlighting their roles in cellular ...
Cong Jiang, Xiao Tan, Jiali Jin, Ping Wang   +3 more
wiley   +1 more source

Molecular analyses of neurogenic defects in a human pluripotent stem cell model of fragile X syndrome

Brain : a journal of neurology, 2017
Michael J. Boland, Kristopher L. Nazor, H. Tran, A. Szücs, Candace L. Lynch, R. Paredes, F. Tassone, P. Sanna, R. Hagerman, J. Loring   +9 more
semanticscholar   +1 more source

Multifunctional Infrared Polarizer Based on Aligned Growth of High‐Density Boron Nitride Nanotubes

Advanced Science, EarlyView.
This paper presents a novel method for the high‐density, aligned growth synthesis and purification of boron nitride nanotubes (BNNTs). The polarization sensitivity and linear dichroism characteristics of BNNTs in the near‐infrared and mid‐infrared bands are comprehensively verified.
Ningqiang Shi, Xiaofei Xiao, Mingyu Zhang, Zhijun Li, Chuncheng Ban, Jinchang Meng, Nannan Shi, Mingyang Wu, Zebo Zheng, Ling Li   +9 more
wiley   +1 more source

Selective Deletion of Astroglial FMRP Dysregulates Glutamate Transporter GLT1 and Contributes to Fragile X Syndrome Phenotypes In Vivo

Journal of Neuroscience, 2016
Haruki Higashimori, Christina S. Schin, C. S. R. Ming, Lydie J. Morel, Temitope Shoneye, D. Nelson, Yongjie Yang   +6 more
semanticscholar   +1 more source

Trinucleotide repeat expansion and RNA dysregulation in fragile X syndrome: emerging therapeutic approaches. [PDF]

RNA
Jung S, Richter JD.
europepmc   +1 more source