Results 31 to 40 of about 5,538,805 (353)
Fragile Phases As Affine Monoids: Classification and Material Examples [PDF]
Phys. Rev. X 10, 031001 (2020), 2019 Topological phases in electronic structures contain a new type of topology, called fragile, which can arise, for example, when an Elementary Band Representation (Atomic Limit Band) splits into a particular set of bands. We obtain, for the first time, a complete classification of the fragile topological phases which can be diagnosed by symmetry ...
arxiv +1 more source
Fragile X mental retardation protein modulates the stability of its m6A‐marked messenger RNA targets
Human Molecular Genetics, 2018 &NA; N 6‐methyladenosine (m6A) is the most prevalent internal modification of mammalian messenger RNAs (mRNAs) and long non‐coding RNAs. The biological functions of this reversible RNA modification can be interpreted by cytoplasmic and nuclear ‘m6A ...
Feiran Zhang +9 more
semanticscholar +1 more source
Translational Neuroscience, 2017 Fragile X syndrome (FXS) is the leading genetic cause of autism spectrum disorder (ASD) and inherited intellectual disability (ID) worldwide. Preclinical successes in understanding the biology of FXS have led to numerous translational attempts in human ...
Duy Phan Q., Budimirovic Dejan B.
doaj +1 more source
Chloride imbalance in Fragile X syndrome
Frontiers in Neuroscience, 2022 Developmental changes in ionic balance are associated with crucial hallmarks in neural circuit formation, including changes in excitation and inhibition, neurogenesis, and synaptogenesis.
Kaleb Dee Miles, Caleb Andrew Doll
doaj +1 more source
Nature Neuroscience, 2018 To uncover the circuit-level alterations that underlie atypical sensory processing associated with autism, we adopted a symptom-to-circuit approach in the Fmr1-knockout (Fmr1–/–) mouse model of Fragile X syndrome.
Anubhuti Goel +11 more
semanticscholar +1 more source
Fragile X-Associated Neuropsychiatric Disorders (FXAND)
Frontiers in Psychiatry, 2018 Fragile X syndrome (FXS) is caused by the full mutation (>200 CGG repeats) in the Fragile X Mental Retardation 1 (FMR1) gene. It is the most common inherited cause of intellectual disability (ID) and autism.
R. Hagerman +5 more
semanticscholar +1 more source
The Structural Difference Between Strong and Fragile Liquids [PDF]
Journal of Non-Crystalline Solids X 13, 100080 (2022), 2023 A structural order parameter for disordered configurations is defined, based, not on local topologies, but on the degree of local restraint imposed on each atom. This restraint parameter provides a clear distinction between a strong liquid (SiO2) and a fragile liquid (a binary Lennard-Jones mixture) without reference to dynamics.
arxiv
Fragile X Syndrome Recognition
Pediatric Neurology Briefs, 1989 The clinical characteristics of 20 children younger than 7½ years of age with the fragile X syndrome were reviewed at the Cincinnati Center for Developmental Disorders, Children’s Hospital Medical Center, University of Cincinnati College of Medicine ...
J Gordon Millichap
doaj +1 more source
Activation of autophagy rescues synaptic and cognitive deficits in fragile X mice
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and is a leading genetic cause of autism. The mammalian target of rapamycin (mTOR) complex 1 cascade is a central regulator of protein translation, cell ...
Jingqi Yan +4 more
semanticscholar +1 more source
Journal of Neurodevelopmental Disorders, 2019 Background Fragile X syndrome (FXS) is characterized by a range of developmental, neuropsychiatric, and behavioral symptoms that cause significant impairment in those with the disorder.
Helen Heussler +7 more
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