Results 101 to 110 of about 297,713 (300)

Compressing nearly hard sphere fluids increases glass fragility

open access: yes, 2009
We use molecular dynamics to investigate the glass transition occurring at large volume fraction, phi, and low temperature, T, in assemblies of soft repulsive particles.
Allen M.   +4 more
core   +3 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

A Fragility Framework for Surface Erosion With Application to Earthen Dam Breaching

open access: yesWater Resources Research
Overtopping failures of earthen dams are a growing concern under intensifying extreme rainfall. This study introduces a probabilistic fragility framework that combines hydrologic modeling, hydraulic analysis, and soil erodibility to assess erosion risk ...
Ege C. Kurter   +3 more
doaj   +1 more source

Cross-comparative analysis of evacuation behavior after earthquakes using mobile phone data

open access: yes, 2018
Despite the importance of predicting evacuation mobility dynamics after large scale disasters for effective first response and disaster relief, our general understanding of evacuation behavior remains limited because of the lack of empirical evidence on ...
Ikemoto, Satoshi   +3 more
core   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Financial Fragility and Banking Sector in a Macroeconomic Model with Minskyan Insights [PDF]

open access: yes, 2010
In light of the recent global financial crisis, the notion of financial fragility has become a cornerstone in current research programs of the dynamics of modern monetary production economies.
Nikolaidi, Maria
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

In Time of Troubles: Challenges and Prospects in the Middle East and North Africa [PDF]

open access: yes
The recent crises concerning food and finances highlight the extreme fragility of the MENA countries and question the sustainability of the development processes.
Imed Drine
core  

Demonstrating adequate safety for a concrete column exposed to fire, using probabilistic methods [PDF]

open access: yes, 2019
Demonstrating adequate safety for exceptional designs and new design applications requires an explicit evaluation of the safety level, considering the uncertainties associated with the design. The recently published PD 7974-7:2019 provides five routes to
Elhami Khorasani, Negar   +3 more
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

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