Results 41 to 50 of about 96,454 (308)

Fragility Analysis of Gantry Crane Subjected to Near-Field Ground Motions

Applied Sciences, 2020
A gantry crane located in a near-field earthquake-prone area is selected in this paper as an example, and the nonlinear finite element (FE) model is used considering the material nonlinearity including plastic hinges and the second order (P − Δ ...
Qihui Peng, Wenming Cheng, Hongyu Jia, Peng Guo   +3 more
doaj   +1 more source

Influence of the Number of Ground Motions on Fragility Analysis of 5 MW Wind Turbines Subjected to Aerodynamic and Seismic Loads Interaction

Energies, 2022
In this paper, the influence of the number of ground motions on fragility analysis of 5 MW wind turbines under the excitation of aerodynamic and seismic loads is investigated to acquire the sufficient number of records for reasonable fragility estimation.
Chenyang Yuan, Yunfei Xie, Jing Li, Weifeng Bai, Haohao Li   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Fragility and Seismic Performance Assessment of RC Frames Under Chinese and Pakistani Building Codes

CivilEng
The increasing integration of Chinese-engineered infrastructure in Pakistan under the China–Pakistan Economic Corridor (CPEC) necessitates a comparative evaluation of seismic resilience between the Chinese and Pakistani building codes. This study focused
Muhammad Usama Aslam, Tariq Umar, Musaab Suliman, Muhammad Usman Siddiq, Hamid Rajabnejad, Ambar Farooq   +5 more
doaj   +1 more source

Seismic Performance Target and Fragility of Masonry Infilled RC Frames under In-Plane Loading

Buildings, 2022
Masonry infilled RC frames are one of the most common structural forms, the damage of which, in earthquake events, usually cause serious losses. The determination of the seismic performance target is the key foundation of performance-based seismic ...
Chunhui Liu, Bo Liu, Xiaomin Wang, Jingchang Kong, Yuan Gao   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Selection of Ground Motion Intensity Measures in Fragility Analysis of a Mega-Scale Steel Frame Structure at Separate Limit States: A Case Study

Buildings, 2022
Selecting an appropriate ground motion intensity measure (IM) to estimate the aleatory uncertainty produced by ground motion variability is the first and crucial step in fragility analysis. The choice of IM is influenced not only by the structural system
Yantai Zhang, Ruihan Shen, Baoyin Sun, Tingting Liu, Yongan Shi, Luyao Li   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analysis and Evaluation to a State’s Fragility

International Journal of Modern Nonlinear Theory and Application, 2018
Climate change is a global focus over the decades. It triggers many environment issues frequently, even serious natural disasters. The potential effects of the climate change are worse than itself. Many of these effects will gradually weaken the structure of society and government. As a result, the broken governments will turn into fragile states which
Zirui Su, Yuting Nie, Fei Xie
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source