Results 51 to 60 of about 96,454 (308)

Effect of Ground Motion Duration and Frequency Characteristics on the Probabilistic Risk Assessment of a Concrete Gravity Dam

open access: yesInfrastructures
Evaluation of seismic risk by capturing the influences of strong motion duration and frequency contents of ground motion through probabilistic approaches is the main element of this study.
Tahmina Tasnim Nahar   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Fragility analysis of underground large-scale frame structures considering seismic effects of vertical earthquakes

open access: yesYantu gongcheng xuebao, 2023
The increase dynamic analysis (IDA) curves of seismic responses of the underground large-scale frame structure (ULSFS) are investigated during the single horizontal earthquakes and horizontal-vertical earthquakes, respectively. The influence mechanism of
QIU Dapeng 1, 2, CHEN Jianyun 3, WANG Wenming 1, 2, CAO Xiangyu 4
doaj   +1 more source

Adaptive artificial neural networks for seismic fragility analysis [PDF]

open access: yes2017 2nd International Conference on System Reliability and Safety (ICSRS), 2017
In seismic probabilistic risk assessment, fragility curves are used to estimate the probability of failure of a structure or its critical components at given values of seismic intensity measures, e.g. the peak ground acceleration. However, the computation of the fragility curves requires a large number of time-consuming mechanical simulations with the ...
Wang, Zhiyi   +3 more
openaire   +4 more sources

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Methodical Investigations on Seismic Retrofitting of Steel Plate Shear Wall Systems

open access: yesBuildings
An efficient retrofitting technique is expected to improve the seismic performance of a lateral force-resisting system without increasing the seismic demand on the structure, which can unfavorably lead to irreparable damages during a seismic event.
Tadeh Zirakian
doaj   +1 more source

Seismic Fragility Assessment of Steel SMRF Structures under Various Types of Near and Far Fault Ground Motions [PDF]

open access: yesJournal of Rehabilitation in Civil Engineering, 2019
In this paper, the seismic collapse probability of special steel moment-resisting frame (SSMRF) structures, designed to 4th edition of Iranian seismic design code, under near fault pulse-like and far fault ordinary ground motions is evaluated through ...
Morteza Razi   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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