Results 101 to 110 of about 8,391,091 (301)

Revealing the role of molecular rigidity on the fragility evolution of glass-forming liquids

Nature Communications, 2016
The fragility describes the degree of slowdown in material dynamics as approaching glass transition temperature, but its molecular origin remains unclear.
C. Yildirim, J.-Y. Raty, M. Micoulaut
doaj   +1 more source

The weakness of fragility index exposed in an analysis of the traumatic brain injury management guidelines: A meta-epidemiological and simulation study

PLoS ONE, 2020
Objectives To perform fragility index (FI) analysis on the evidence that forms the basis of the guidelines for the management of severe traumatic brain injury (TBI), and develop a deeper understanding of the pitfalls associated with FI.
T. M. Condon, Richard W Sexton, A. Wells, Minh-Son To   +3 more
semanticscholar   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Randomized controlled trial outcomes for nonoperative management of lateral epicondylitis of the elbow are statistically fragile: a systematic review

JSES Reviews, Reports, and Techniques
Background: Nonoperative management remains the first line treatment for lateral epicondylitis of the elbow. In this study, we evaluated the reliability of outcomes reported in randomized controlled trials (RCTs) focusing on nonoperative therapies using ...
Reanna Shah, BS, Alexander Yu, BS, Mary Grace Kelley, MS, Avanish Yendluri, BS, Dennis Bienstock, MD, Katrina Nietsch, MS, Michael N. Megafu, MPH, Xinning Li, MD, John D. Kelly, IV, MD, Robert L. Parisien, MD   +9 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Geriatric nutritional risk index as a predictor for fragility fracture risk in elderly with type 2 diabetes mellitus: A 9-year ambispective longitudinal cohort study.

Clinical Nutrition
BACKGROUND & AIMS The elderly are prone to fragility fractures, especially those suffering from type 2 diabetes mellitus (T2DM) combined with osteoporosis.
Jiangmei Pan, Guo-Ling Xu, Zhen-Wei Zhai, Jingxia Sun, Qiu Wang, Xiuxian Huang, Yanli Guo, Quan Lu, Jian-Ming Mo, Y. Nong, Jian-Hao Huang, Wen-Sheng Lu   +11 more
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Fragile Definition of State Fragility [PDF]

We investigates the link between fragility and economic development in sub-Saharan Africa over a yearly panel including 28 countries for the 1999-2004 period.
Graziella Bertocchi, Andrea Guerzoni
core  

DETERMINAN PREDIKSI KRISIS PERBANKAN BERBASIS BANKING SECTOR FRAGILITY INDEX [PDF]

, 2018
The unfavorable condition of the banking system has a major impact on the economy in Indonesia. The existence of monthly BSF (Banking Sector Fragility) index can be used to decide whether the national banking system is experiencing crisis at some point ...
Ahmar, Nurmala, Hamida, Dian, Djaddang, Syahril   +2 more
core   +1 more source

Fragility of Observed Associations in Selection of Empirical Antifungal Therapy for Critically Ill Non-Neutropenic Patients [Letter]

Infection and Drug Resistance
Saba ManzoorDaniele Roberto GiacobbeRonald ChowDepartment of Medicine, University of Toronto, Toronto, Ontario, CanadaDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, ItalyClinica Malattie Infettive, Azienda Ospedaliera Metropolitana ...
Manzoor S, Giacobbe DR, Chow R
doaj