Results 61 to 70 of about 4,896,431 (278)
State fragility and economic vulnerability: what is measured and why? [PDF]
State fragility is a concept that emerged among the international community of donors in order to adapt aid policies to particularly difficult situations.
Sylviane GUILLAUMONT JEANNENEY +1 more
core +2 more sources
Diabetology & Metabolic SyndromeBackground The triglyceride-glucose (TyG) index, a recognized marker for insulin resistance, holds potential implications for skeletal health. However, its relationship with fragility fractures remains uncertain.
Yuan Lou +4 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Fragility Index in Cardiovascular Randomized Controlled Trials [PDF]
Circulation: Cardiovascular Quality and Outcomes, 2019 Background: Efficacy of an intervention is commonly evaluated using P values, in addition to effect size measures such as absolute risk reduction, relative risk reduction, and numbers needed to treat.
Muhammad Shahzeb, Khan +9 more
openaire +2 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Fast and direct determination of fragility in metallic glasses using chip calorimetry
Heliyon, 2019 We directly determine the thermodynamic fragility index of two metallic glasses (Mg65Cu25Gd10 and Au49Cu26.9Si16.3Ag5.5Pd2.3) from fictive temperature shifts induced by a variation of the quenching rate using fast differential scanning calorimetry (FDSC).
Florian Spieckermann +5 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Robustness Index: Going Beyond Statistical Significance by Quantifying Fragility [PDF]
, 2023 Statistical significance is widely used to evaluate research findings but has limitations around reproducibility. Measures of statistical fragility aim to quantify robustness against violations of assumptions.
Heston, Thomas F
core
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source