Results 111 to 120 of about 4,409,486 (250)

Humanized VHH-hFc Fusion Proteins Targeting the L-HN Fragment of Tetanus Toxin Provided Protection In Vivo

Antibodies
Background: Tetanus toxin, produced by Clostridium tetani, is the second deadliest known toxin. Antibodies capable of neutralizing tetanus toxin (TeNT) are vital for preventing and treating tetanus disease.
Yating Li, Kexuan Cheng, Jiazheng Guo, Yujia Jiang, Qinglin Kang, Rong Wang, Peng Du, Chen Gao, Yunzhou Yu, Zhixin Yang, Wei Wang, Jiansheng Lu   +11 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Local Immune Activation and Age Impact on Humoral Immunity in Mice, with a Focus on IgG Sialylation

Vaccines
Age alters the host’s susceptibility to immune induction. Humoral immunity with circulating antibodies, particularly immunoglobulin G (IgG), plays an essential role in immune response.
Priti Gupta, Tibor Sághy, Miriam Bollmann, Tao Jin, Claes Ohlsson, Hans Carlsten, Carmen Corciulo, Cecilia Engdahl   +7 more
doaj   +1 more source

Columbia Region handbook

, 1980
Presents a general overview of the Columbia Region, its organization and its people, and some basic information about the region's fish and wildlife and their management.This archived document is maintained by the State Library of Oregon as part of the ...

core  

A Dispersant‐Driven Carbon‐Binder Domains Homogeneity in High‐Energy‐Density Electrodes for Lithium‐Ion Batteries

Advanced Science, EarlyView.
A polar dispersant, aromatic‐functionalized polyacrylate (AFPA), enables the formation of a uniform CBD network by enhancing miscibility with PVDF and suppressing phase separation. This leads to α‐phase crystallization of PVDF and aligned CNT networks within the CBD, resulting in well‐connected structures that improve cohesion, electron/ion transport ...
Da‐Sol Kwon, Min Young Seo, Jinho Ahn, Yea‐Ji Jeong, Woohyeon Shin, Wonseok Ko, Min Jeong Kim, Jiny Lee, Won‐Yong Jeon, Min‐Jae Choi, Kwang In Kim, Jin Ju Eom, Sang Yeop Oh, Honghee Lee, Joona Bang, Jongsoon Kim, YongJoo Kim, Jung‐Keun Yoo   +17 more
wiley   +1 more source

Bivalent circular RNA vaccines against porcine epidemic diarrhea virus and transmissible gastroenteritis virus

Frontiers in Immunology
Porcine Epidemic Diarrhea Virus (PEDV) and Transmissible Gastroenteritis Virus (TGEV) pose significant threats to neonatal piglets, leading to severe diarrhea and potentially lethal consequences.
Weibing Zhang, Weibing Zhang, Lei Wang, Lei Wang, Liyu Chu, Xu Ma, Xu Ma, Wenjing Gao, Wenjing Gao, Yarong Wu, Yongfeng Qiao, Yongfeng Qiao, Xianjun Wang, Xianjun Wang, Lu Zhao, Lu Zhao, Hong Hu, Hong Hu, Xiaoyu Li, Ding Zhang, Tao Song, Guocan Yu, Haidong Wang, Chunbo Dong, Chunbo Dong, Zhida Liu, Zhida Liu   +26 more
doaj   +1 more source

Biotechnological applications of the eukaryotic parasite L. tarentolae.

, 2019
L. tarentolae is used to study RNA editing (A), gene amplification (B), vaccine development against human-pathogenic Leishmania species (C), and recombinant (human) protein production (D).
Larry Simpson (774451), Dmitri A. Maslov (7041650), Zoltán Konthur (115953), Stephan Klatt (420692)   +3 more
core   +1 more source

From Fluoride Removal to Interfacial Reactivity Enhancement: Functionalized La3+‐Crosslinked B/CuO Energetic Microspheres

Advanced Science, EarlyView.
A fluoride adsorption‐functionalization strategy directly couples fluoride wastewater remediation with combustion performance enhancement of B/CuO energetic microspheres. Fluoride captured from wastewater is retained within the microspheres without adsorbent regeneration or disposal, simultaneously achieving pollutant removal and enhanced energetic ...
Hongbiao Huo, Minghao Bao, Zhongbo Han, Wei Shi, Jianyong Xu, Pengfei Cui, Wenchao Zhang   +6 more
wiley   +1 more source

Antibody–Antibiotic Conjugates: Mechanisms, Clinical Progress, and Next‐Generation Strategies Against Multidrug‐Resistant Bacterial Infections

MicrobiologyOpen
The rise of multidrug‐resistant (MDR) bacterial pathogens presents a critical challenge to global health, highlighting the need for innovative therapeutic strategies beyond conventional antibiotics.
Parvin Askari, Soudabeh Eshaghi, Leila Omidvar, Motahareh Mahi‐Birjand   +3 more
doaj   +1 more source

Specific Conjugation of the Hinge Region for Homogeneous Preparation of Antibody Fragment-Drug Conjugate: A Case Study for Doxorubicin-PEG-anti-CD20 Fab' Synthesis

, 2016
Conventional preparation strategies for antibody-drug conjugates (ADCs) result in heterogeneous products with various molecular sizes and species.
Guanghui Ma (1428790), Zhiguo Su, Zhiguo Su (381311), Jing Zhang, Ma, Guanghui, Su, Zhiguo, Guanghui Ma, Zhang, Jing, Zhan Zhou, Yan Zhang (8098), Jing Zhang (23775), Yan Zhang, Zhang, Yan, Zhan Zhou (619006), Zhou, Zhan   +14 more
core   +1 more source