The tetravalent, bispecific properties of FS118, an anti-LAG-3/PD-L1 antibody, mediate LAG-3 shedding from CD4 + and CD8 + tumor-infiltrating lymphocytes. [PDF]
Anticancer DrugsReader CS +6 more
europepmc +1 more source
Designing PLA/PHBV Implants With Degradation Matched to Normal or Inflammatory Tissues
Journal of Applied Polymer Science, EarlyView.PLA/PHBV blends are investigated under simulated normal and pathological conditions. Multivariate statistical analysis decouples the competing effects of water‐uptake‐driven hydrolysis and crystallinity‐imposed barriers. Melt‐state rheological parameters serve as structural probes linking phase morphology to degradation kinetics. A semi‐empirical model
Luyao Gao +2 more
wiley +1 more source
Effect of ADCC-enhancing mutations on N-glycan profiles of human IgG1 antibodies. [PDF]
Biochem JHan L, Jiang H, Chiu ML.
europepmc +1 more source
Advanced Physics Research, EarlyView.A correlation between thermal treatment and enhanced crystalline quality, surface morphology, and optical response. As annealing temperature increases, structural refinement (evidenced by phrase transition from hexagonal to cubic), and more defined morphology (seen via SEM), and improved optical absorption and bandgap tuning (UV–vis and PL spectra) are
Vanthini Nelson Adoons +2 more
wiley +1 more source
Vascular endothelial growth factor-A and drug level in serum and human breast milk of a lactating woman after intravitreal injection of ranibizumab: a case report. [PDF]
Front Med (Lausanne)Zhang J +5 more
europepmc +1 more source
Between public service and market: Portraying the bifront university in a platformized world
British Educational Research Journal, EarlyView.Abstract This paper contributes to the international debate on the changes affecting recruitment and orientation processes toward higher education. Based on qualitative research involving 19 Italian public universities, the study analyses the transformations in communication, recruitment and orientation activities within platformization and increasing ...
Marco Pitzalis +2 more
wiley +1 more source
Expanding the horizons of cancer therapy with next-generation 4-1BB agonists: a review of molecular and clinical strategies to maximize efficacy and ensure safety. [PDF]
MAbsYou G +7 more
europepmc +1 more source
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
BMEMat, EarlyView.Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
Isolation of neutralizing antibodies against SARS-CoV-2 through an epitope-guided negative screening by phage display. [PDF]
J Biomed ResLu M +8 more
europepmc +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
BMEMat, EarlyView.Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source