Results 211 to 220 of about 8,200 (248)

An integrated cell and medium engineering approach for production of a nanobody fusion in Saccharomyces cerevisiae. [PDF]

Appl Microbiol Biotechnol
Niemelä LRK, Kirjavainen LM, Kozlowski HCJ, Salminen H, Frey AD.   +4 more
europepmc   +1 more source

Between public service and market: Portraying the bifront university in a platformized world

British Educational Research Journal, EarlyView.
Abstract This paper contributes to the international debate on the changes affecting recruitment and orientation processes toward higher education. Based on qualitative research involving 19 Italian public universities, the study analyses the transformations in communication, recruitment and orientation activities within platformization and increasing ...
Marco Pitzalis, Ciro Cangiano, Alessandro Lovari   +2 more
wiley   +1 more source

Structural basis of nectin-4 recognition by the antibody-drug conjugate 9MW2821. [PDF]

J Biol Chem
Fang P, You M, Wen H, Cao Y, Zhou W, Zhu X, Shi L, Sun X, Li K, Li W, Wang J, Wu H, Tan X.   +12 more
europepmc   +1 more source

A Review on Quantitative Process Analytical Technology for Continuous Downstream Processing of Monoclonal Antibodies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The competition in the biopharmaceutical market is increasing due to the market entry of biosimilars and rising costs in research and development of new drugs. Hence, continuous manufacturing gained significant attention due to its potential in reducing production cycle times and costs, as well as the possibility of real‐time release testing ...
Mariana Carvalho, Ana Cruz, Cees Haringa, Marcel Ottens, Marieke Klijn   +4 more
wiley   +1 more source

Discovery and computational characterization of ZIKV envelope-targeted peptides from a subtractive phage display library. [PDF]

PLoS One
Burciaga-Flores M, Wong-Romero J, Elizondo-Quiroga D, Villalobos-Sánchez E, Gutiérrez-Ortega A, Camacho-Villegas TA, Águila SA.   +6 more
europepmc   +1 more source

Quantitative Analysis Reveals Hitchhiking Drives Polysorbate Hydrolase Persistence Via Host Cell Protein–Antibody Interactions

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Polysorbate‐degrading host cell proteins (HCPs) represent a critical challenge in the manufacturing of monoclonal antibody therapeutics due to their potential to persist during downstream processing. While their enzymatic activity has been characterized, the role of direct HCP‐mAb interactions, particularly those involving polysorbate ...
Melanie Maier, Lukas Griesinger, Matthias Franzreb, Simon Kluters   +3 more
wiley   +1 more source

Successful treatment of lung squamous cell carcinoma with envafolimab, a PD-L1 inhibitor combined with chemotherapy: a case report. [PDF]

Transl Cancer Res
Sun X, Tang Y, Zhu Y, Wei J, Zhang X, Osoegawa A, Berardi R, Yamaguchi F, Cheng H.   +8 more
europepmc   +1 more source

In situ biomimetic materials for dentin repair

BMEMat, EarlyView.
This review primarily discusses the role and clinical application of key biomimetic materials for in situ dentin repair, providing a feasible foundation for future material and performance optimization in situ dentin regeneration. Abstract Dental defects, ranking among the most prevalent diseases globally, pose a serious threat to human health, with ...
Jingjing Deng, Siyi Ren, Xuliang Deng, Yan Wei   +3 more
wiley   +1 more source

A novel <i>in vitro</i> serum stability assay for antibody therapeutics incorporating internal standards. [PDF]

MAbs
Li Y, Villafuerte-Vega R, Shenoy VM, Jackson HM, Wang Y, Parrish KE, Jenkins GJ, Sarvaiya H.   +7 more
europepmc   +1 more source

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

BMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim, Hak Yong Kim, Ja Hoon Koo, Gi Doo Cha, Dae‐Hyeong Kim, Hye Jin Kim   +5 more
wiley   +1 more source