Improvements in no evidence of disease activity with ublituximab vs. teriflunomide in the ULTIMATE phase 3 studies in relapsing multiple sclerosis. [PDF]
Alvarez E+13 more
europepmc +1 more source
Two Key Ferredoxins for Nitrogen Fixation Have Different Specificities and Biophysical Properties
Two ferredoxins, FdC and FdN, are collectively essential for the process of nitrogen fixation by the iron nitrogenase in R. capsulatus. We explore the biophysical factors, through spectroscopic and structural characterizations, which determine ferredoxin functionality and pathway specificity. The structure of FdC (PDB: 9I2A) and model of FdN (AF‐D5ARY6)
Holly Addison+5 more
wiley +1 more source
Role of Xenosialylation in Post-Infectious and Post-Vaccination Complications, Including Covid-19 and Anti-SARS-CoV-2 Vaccination. [PDF]
Carnevali F, Mangiaterra S, Rossi G.
europepmc +1 more source
Synthesis and Reactivity of Triphosphaallyl Cation Stabilized by N‐Heterocyclic Carbenes
Imidazoliumyl‐substituted triphosphaallyl cations undergo selective P–C bond cleavage and form unprecedented bicyclic P₃‐Ga scaffolds with unique reactivity. Abstract Reduction of the triphosphaallyl species 6[GaCl4] with GaI[Ga2Cl7] affords the imidazoliumyl‐substituted (L) bicyclo[2.1.1]‐triphosphane 10[Ga2Cl7], featuring an unprecedented Ga2Cl5 ...
Julia Frötschel‐Rittmeyer+8 more
wiley +1 more source
Application and future prospects of bispecific antibodies in the treatment of non-small cell lung cancer. [PDF]
Wen J+6 more
europepmc +1 more source
A Molecular Basis for Antibody Specificity Crystal Structures of IgE-Allergen and IgG-Hapten Complexes [PDF]
Niemi, Merja
core
The stereochemical diversity of the “glycan code” enables similar chiral motifs to arise from both D‐ and L‐sugars. Focused on DC‐SIGN–glycan recognition, two diverse monosaccharide scaffolds, D‐Man (D‐Rha) and L‐Gal (L‐Fuc), maintain the exquisite stereochemistry encoded in the minimal binding epitope.
J. Daniel Martínez+7 more
wiley +1 more source
Novel single-chain fragment variable antibody targeting plasma membrane epitopes on porcine Y-chromosome-bearing sperm. [PDF]
Thongkham M+6 more
europepmc +1 more source
Redox‐Induced Structural Rearrangement in an M8L2 Self‐Assembly
An electron‐rich ligand, based on the so‐called exTTF moiety, self‐assembles with a bimetallic ruthenium complex to provide an M8L2 architecture, where the two ligands adopt a perpendicular orientation. Thanks to the unique electronic and geometric features of the exTTF core, this discrete structure undergoes a structural transformation into a new ...
Jennifer Bou Zeid+7 more
wiley +1 more source