Results 71 to 80 of about 7,556 (242)

Identification of mpox M1R and B6R monoclonal and bispecific antibodies that efficiently neutralize authentic mpox virus

Emerging Microbes and Infections
In 2022, the monkeypox virus (mpox virus, MPXV) exhibited global dissemination across six continents, representing a notable challenge owing to the scarcity of targeted antiviral interventions.
Zuning Ren, Mengjun Li, Jiayin Chen, Xiaohua Gong, Shuo Song, Delin Li, Minghui Yang, Jianhai Yu, Sadia Asghar, Yanxin Cui, Shiyu Niu, Zhonghui Liao, Yushan Jiang, Jiahui Liu, Yuqing Li, Bao Zhang, Wei Zhao, Jie Peng, Yang Yang, Chenguang Shen   +19 more
doaj   +1 more source

Regulating the Interphase Strain in High‐Entropy Oxide Thin Films – An Approach to Attaining Giant Energy Storage Capability under Moderate Electric Fields

Advanced Functional Materials, EarlyView.
This work demonstrates an interphase strain engineering strategy to regulate capacitive energy storage performance in high‐entropy oxide thin films. Through introducing pyrochlore nanocolumns, the polarization response of perovskite unit cells is strengthened, yielding recoverable energy densities up to 93 J cm−3 with an efficiency of 83% under ...
Hao Luo, Yunlong Sun, Haotian Wen, Richard Webster, Yasuhiro Sakamoto, Zizheng Song, Yating Ran, Chenlu Jiang, Siyuan Zhang, Zibin Chen, Shery L. Y. Chang, Danyang Wang   +11 more
wiley   +1 more source

Leishmania tarentolae: taxonomic classification and its application as a promising biotechnological expression host

, 2019
In this review, we summarize the current knowledge concerning the eukaryotic protozoan parasite Leishmania tarentolae, with a main focus on its potential for biotechnological applications.
Klatt, S., Konthur, Z., Maslov, D., Simpson, L.   +3 more
core   +1 more source

Enhancing Direct Solar Water Splitting via ALD of Multifunctional TiO2/Pt Nanoparticle Coatings With Engineered Interfaces to GaAs/GaInP Tandem Cells

Advanced Functional Materials, EarlyView.
Multifunctional atomic layer deposited coatings and interface treatments enhance direct solar water splitting on GaAs/GaInP tandem cells. Optimized TiO2/Pt nanoparticle bilayers ensure durability and catalytic efficiency with minimal optical losses, while H2 plasma pretreatments maximize photovoltage and interfacial charge extraction.
Tim F. Rieth, Verena Streibel, Oliver Bienek, Sergej Levashov, Johannes Dittloff, Kristof Möller, Johanna Eichhorn, Matthias M. May, Ian D. Sharp   +8 more
wiley   +1 more source

Expression of Colorectal Cancer Antigenic Protein Fused to IgM Fc in Chinese Cabbage (Brassica rapa)

Plants, 2020
The epithelial cell adhesion molecule (EpCAM) is a tumor-associated antigen and a potential target for tumor vaccine. The EpCAM is a cell-surface glycoprotein highly expressed in colorectal carcinomas.
Ye-Rin Lee, Chae-Yeon Lim, Sohee Lim, Se Ra Park, Jong-Pil Hong, Jinhee Kim, Hye-Eun Lee, Kisung Ko, Do-Sun Kim   +8 more
doaj   +1 more source

Structural characterization of GASDALIE Fc bound to the activating Fc receptor FcγRIIIa [PDF]

, 2016
The Fc region of Immunoglobulin G (IgG) initiates inflammatory responses such as antibody-dependent cell-mediated cytotoxicity (ADCC) through binding to activating Fc receptors (FcγRI, FcγRIIa, FcγRIIIa).
Ahmed, Alysia A., Bjorkman, Pamela J., Keremane, Sravya R., Vielmetter, Jost   +3 more
core   +2 more sources

Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers

Advanced Healthcare Materials, EarlyView.
The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao, Zheng Zhang, Xincai Wu, Yanwei Chen, Wenjun Li, Jiayan Bao, Xin Zhang, Baoding Chen   +7 more
wiley   +1 more source

Modulation of Dengue/Zika Virus Pathogenicity by Antibody-Dependent Enhancement and Strategies to Protect Against Enhancement in Zika Virus Infection

Frontiers in Immunology, 2018
Antibody-dependent enhancement (ADE) is a phenomenon in which preexisting poorly neutralizing antibodies leads to enhanced infection. It is a serious concern with mosquito-borne flaviviruses such as Dengue virus (DENV) and Zika virus (ZIKV).
Rekha Khandia, Ashok Munjal, Kuldeep Dhama, Kumaragurubaran Karthik, Ruchi Tiwari, Yashpal Singh Malik, Raj Kumar Singh, Wanpen Chaicumpa   +7 more
doaj   +1 more source

Forced Degradation Testing as Complementary Tool for Biosimilarity Assessment [PDF]

, 2019
Oxidation of monoclonal antibodies (mAbs) can impact their efficacy and may therefore represent critical quality attributes (CQA) that require evaluation.
Dyck, Yan Felix Karl, Jabs, Wolfgang, Joseph, Jan Felix, Parr, Maria Kristina, Rehm, Daniel, Sandig, Volker, Winkler, Karsten   +6 more
core   +1 more source

Peptide Display Directed Assembly of Biopolymer Core–Silica Shell Particles

Advanced Healthcare Materials, EarlyView.
Bacterial cells are engineered to produce biopolyester particles displaying peptides mediating growth of silica. Peptide‐coated biopolyester particles are treated with silica precursors and silica shell formation is studied. Transmission electron microscopy shows silica‐coated BPs which are formed after the silicification treatment. Characterization of
Deeptee Chandrashekhar Pande, Frank Sainsbury, Bernd H. A. Rehm   +2 more
wiley   +1 more source