Results 91 to 100 of about 1,331,169 (299)
Fragmentation Phenomena, 1995 Saclay-T93/075 Email: pesch@amoco.saclay.cea ...
openaire +2 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
, 2008 Jet fragmentation functions measured in e^+e^- and p+\bar{p} experiments are well-described on an inclusive hadron level by QCD-based calculations.
B. Abelev +11 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Recent Progress on Perturbative QCD Fragmentation Functions [PDF]
, 1995 The recent development of perturbative QCD (PQCD) fragmentation functions has strong impact on quarkonium production. I shall summarize $B_c$ meson production based on these PQCD fragmentation functions, as well as, the highlights of some recent ...
Cheung, Kingman
core +3 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Land Cover Change in the Andes of Southern Ecuador—Patterns and Drivers
Remote Sensing, 2015 In the megadiverse tropical mountain forest in the Andes of southern Ecuador, a global biodiversity hotspot, the use of fire to clear land for cattle ranching is leading to the invasion of an aggressive weed, the bracken fern, which is threatening ...
Giulia F. Curatola Fernández +6 more
doaj +1 more source
Asymptotic behavior of the growth-fragmentation equation with bounded fragmentation rate
, 2016 We are interested in the large time behavior of the solutions to the growth-fragmentation equation. We work in the space of integrable functions weighted with the principal dual eigenfunction of the growth-fragmentation operator.
Bernard, Etienne, Gabriel, Pierre
core +3 more sources