Results 41 to 50 of about 723,628 (294)
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Edwards, Keith, Farr, Graham
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Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
In this thematic issue of Svetovi/Worlds: Journal for Ethnology, Anthropology and Folkloristics, we explore the complex cultural and social worlds that characterise our daily lives and that are often presented as isolated.
Tomislav Oroz, Peter Simonič
doaj +1 more source
Patch Size and Population Density: the Effect of Immigration Behavior
Many habitat fragmentation experiments make the prediction that animal population density will be positively related to fragment, or patch, size. The mechanism that is supposed to result in this prediction is unclear, but several recent reviews have ...
Jeff Bowman +2 more
doaj +1 more source
DAVID JONES’ THE ANATHEMATA: IS MODERN EPIC POSSIBLE? [PDF]
The epic poem is a problematic genre in the modern era, and might be regarded as having ceased to thrive in Western Literature since the Renaissance. Attempts have been made in criticism to assert that the genre of the epic poem has been replaced by the
Martin Potter
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Industrialized construction faces persistent fragmentation challenges that negatively impact project performance. Although there is consensus on the importance of integration, its effective adoption in industrialized construction, particularly for ...
Harrison Mesa +3 more
doaj +1 more source
Cumulative Effects of Barriers on the Movements of Forest Birds
Although there is a consensus of opinion that habitat fragmentation has deleterious effects on animal populations, primarily by inhibiting dispersal among remaining patches, there have been few explicit demonstrations of the ways by which degraded ...
Marc Bélisle, Colleen Cassady St. Clair
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

