Results 51 to 60 of about 416,094 (266)

The Impact of Flow Velocity on Environmental DNA Detectability for the Application in River Systems

open access: yesEnvironmental DNA
Organisms perpetually release genetic material in their surroundings, referred to as environmental DNA (eDNA), which can be captured and subsequently analyzed to detect biodiversity across the tree of life. In lotic, dynamic environments, little is known
Jelle A. Dercksen   +6 more
doaj   +1 more source

Using structured decision making with landowners to address private forest management and parcelization: balancing multiple objectives and incorporating uncertainty

open access: yesEcology and Society, 2015
Parcelization and forest fragmentation are of concern for ecological, economic, and social reasons. Efforts to keep large, private forests intact may be supported by a decision-making process that incorporates landowners' objectives and uncertainty.
Paige F. B. Ferguson   +3 more
doaj   +1 more source

Structural Characterization of Chemical Compounds Based on Their Fragmentation Rules in Sophorae Fructus by UPLC-QTOF-MS/MS

open access: yesPharmaceutical Fronts, 2022
This study aims to identify the chemical components in Sophorae Fructus, and explore the mass spectrometric cleavage rules using the UPLC-Q-TOF-MS/MS method. The main characteristic fragments of the compounds were analyzed by electrospray ionization (ESI)
Zi-Hui He   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Lack of Agreement on Fragmentation Metrics Blurs Correspondence between Fragmentation Experiments and Predicted Effects

open access: yesEcology and Society, 2003
The direct correspondence between landscape fragmentation and its effects is still the subject of debate. Many widely accepted hypotheses are not supported by experiments. The issue of fragmentation measurement is addressed here.
Jan Bogaert
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Le Mexique s’est-il polarisé ? Changement et continuités d’une géographie électorale plurielle et fragmentée

open access: yesCahiers des Amériques Latines
Since the presidential election of Andrés Manuel López Obrador (AMLO) in 2018, Mexican politics seems to be organized around two irreconcilable antagonistic poles.
Willibald Sonnleitner
doaj   +1 more source

Estimating density and detection of bobcats in fragmented midwestern landscapes using spatial capture–recapture data from camera traps

open access: yesWildlife Society Bulletin, 2019
Camera‐trapping data analyzed with spatially explicit capture–recapture (SCR) models can provide a rigorous method for estimating density of small populations of elusive carnivore species.
Christopher N. Jacques   +7 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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