Results 51 to 60 of about 417,831 (266)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
In this thematic issue of Svetovi/Worlds: Journal for Ethnology, Anthropology and Folkloristics, we explore the complex cultural and social worlds that characterise our daily lives and that are often presented as isolated.
Tomislav Oroz, Peter Simonič
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Industrialized construction faces persistent fragmentation challenges that negatively impact project performance. Although there is consensus on the importance of integration, its effective adoption in industrialized construction, particularly for ...
Harrison Mesa +3 more
doaj +1 more source
Patch Size and Population Density: the Effect of Immigration Behavior
Many habitat fragmentation experiments make the prediction that animal population density will be positively related to fragment, or patch, size. The mechanism that is supposed to result in this prediction is unclear, but several recent reviews have ...
Jeff Bowman +2 more
doaj +1 more source
DAVID JONES’ THE ANATHEMATA: IS MODERN EPIC POSSIBLE? [PDF]
The epic poem is a problematic genre in the modern era, and might be regarded as having ceased to thrive in Western Literature since the Renaissance. Attempts have been made in criticism to assert that the genre of the epic poem has been replaced by the
Martin Potter
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Evaluating the integration methods of the higher education system in Mozambique
The forms of integration and articulation in tertiary education are debated globally, including studies that discuss higher education’s expansion, differentiation, diversity, and fragmentation.
Lucas Lavo António Jimo Miguel +3 more
doaj +1 more source
Cumulative Effects of Barriers on the Movements of Forest Birds
Although there is a consensus of opinion that habitat fragmentation has deleterious effects on animal populations, primarily by inhibiting dispersal among remaining patches, there have been few explicit demonstrations of the ways by which degraded ...
Marc Bélisle, Colleen Cassady St. Clair
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

