Results 61 to 70 of about 723,628 (294)

Estimating density and detection of bobcats in fragmented midwestern landscapes using spatial capture–recapture data from camera traps

open access: yesWildlife Society Bulletin, 2019
Camera‐trapping data analyzed with spatially explicit capture–recapture (SCR) models can provide a rigorous method for estimating density of small populations of elusive carnivore species.
Christopher N. Jacques   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Fragmentation of chromon derivatives using mass spectrometry technique

open access: yes, 2022
In this Thesis work, we studied Chromon derivatives by Bruker micrOTOF -Q ESI-TOF/APCI TOF and mainly APCI in Tandem mode, because for the more informative fragmentation studies usually the protonated molecules (adduct ions) should have been generated ...
Baamer, Ahmed
core  

Le Mexique s’est-il polarisé ? Changement et continuités d’une géographie électorale plurielle et fragmentée

open access: yesCahiers des Amériques Latines
Since the presidential election of Andrés Manuel López Obrador (AMLO) in 2018, Mexican politics seems to be organized around two irreconcilable antagonistic poles.
Willibald Sonnleitner
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

An application of semigroup theory to a fragmentation equation [PDF]

open access: yes, 2004
The process of fragmentation arises in many physical situations, including polymer degradation, droplet breakage and rock crushing and grinding. Under suitable assumptions, the evolution of the size distribution c(x, t), where x represents particle size ...
Lamb, W., Stewart, Iain W., Blair, P.N.
core   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

FRAGMENTATION AND HADRONIZATION [PDF]

open access: yesInternational Journal of Modern Physics A, 2000
31 pages, 33 figures. Plenary talk at XIX International Symposium on Lepton and Photon Interactions at High Energies, Stanford, August ...
openaire   +5 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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