Results 71 to 80 of about 297 (139)

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Computational modeling approaches for circulating cellfree DNA in oncology

International audienceMany cancer patients undergoing immune-checkpoint inhibition (ICI) experience early progression (EP), defined as progression at the first imaging evaluation.
Nguyen Phuong, Linh
core   +3 more sources

Long cell-free DNA fragments predict early-progression in patients with advanced or metastatic cancer treated with immune-checkpoint inhibition.

International audienceBackground: Immune-checkpoint inhibition (ICI) has significantly advanced cancer treatment, but many patients experience early progression (EP).
Boutonnet, Audrey, Nguyen Phuong, Linh, Greillier, Laurent, Gaudy-Marqueste, Caroline, Salas, Sébastien, Garcia, Jean-Charles, Ginot, Frédéric, Deville, Jean-Laurent, Fina, Frédéric, Benzekry, Sébastien   +9 more
core   +1 more source

Abstracts

Cancer Science, Volume 116, Issue S1, Page 1-1975, January 2025.
wiley   +1 more source

Protein-oligopeptide fragmentomics

, 2008
8
openaire   +2 more sources

-fragmentome)

, 2015

core   +2 more sources

Seminal plasma cfDNA fragmentomics landscape delineates male infertility subtypes

Clinical Epigenetics
Abstract Background While cell-free DNA (cfDNA) fragmentomics has transformed liquid biopsy applications in prenatal screening and oncology, its potential in male reproductive health remains uncharted. Methods Through integrated whole-genome sequencing and jagged end sequencing (Jag-Seq) coupled with non-CpG methylation analysis, we ...
Wu, Xiaoyu, Meng, Fan, Zhang, Huiping, Li, Zeqing, Zhao, Kai   +4 more
openaire   +2 more sources

Innovations in Early Lung Cancer Detection: Tracing the Evolution and Advancements in Screening

Lung cancer mortality rates, particularly non-small cell lung cancer (NSCLC), continue to present a significant global health challenge, and the adoption of lung cancer screening remains limited, often influenced by inequities in access to healthcare ...
Demetria Tennefoss, Lisa Carter-Bawa, Caitlin A. Schonewolf, Anil Vachani, Peter B. Bach, Chris Cisar, Ali H. Zaidi, Lindsey B. Cotton   +7 more
core   +1 more source

DeepFRAG: a method for cancer detection based on DNA fragmentomics and deep learning

Bioinformatics Advances
Abstract Motivation Cancer screening using liquid biopsy technology has become standard in modern clinical and preventive oncology. This method analyzes cell-free DNA (cfDNA) circulating in a patient’s bloodstream.
Andrey Koch, Eldar Giladi
openaire   +3 more sources

Cell-Free DNA Fragmentome Dynamics as a Biomarker for Immune-Checkpoint Inhibition in Advanced Carcinoma

International audienceEarly prediction of resistance to immunotherapy is a major challenge in oncology. The ongoing SChISM (Size Cell-fre DNA (cfDNA) Immunotherapies Signature Monitoring) clinical study proposes an innovative approach based on patented ...
Boutonnet, Audrey, Fina, Frederic, Della-Negra, Lucie, Nguyen Phuong, Linh, Tomasini, Pascale, Greillier, Laurent, Garcia, Jean-Charles, Salas, Sébastien, Ginot, Frédéric, Zakrajsek, Romain, Deville, Jean-Laurent, Benzekry, Sébastien   +11 more
core   +1 more source