Results 1 to 10 of about 18,637 (230)
The Nexus of cfDNA and Nuclease Biology [PDF]
Trends in Genetics, 2021 Cell-free DNA (cfDNA) is a widely used noninvasive biomarker for diagnosis and prognosis of multiple disease states. Emerging evidence suggests that cfDNA might not just be passive waste products of cell death but could have a physiological and pathological function in inflammation and autoimmunity.
Diana S.C. Han, Y.M. Dennis Lo
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Diagnostic Value of cfDNA in Pancreatic Cancer
Zhongliu Fangzhi Yanjiu, 2022 Objective To explore the diagnostic value of cfDNA in pancreatic cancer. Methods A total of 467 patients with pancreatic cancer and 129 healthy controls were enrolled. cfDNA concentration was detected using the QuantiDNA Direct cfDNA Test (DiaCarta) kit.
XU Yijun, ZHU Mingchen
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Adoption of a non-invasive prenatal test (NIPT) in prenatal screening in Moscow: first results
Russian Open Medical Journal, 2021 The objective — To assess the effectiveness of including NIPT in the structure of prenatal diagnostics in Moscow. Material and Methods — Totally 5,181 pregnancies undergoing screening for fetal trisomy using NIPT during the period from 01.04.2020 to 30 ...
Anton S. Olenev +7 more
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Plasma cfDNA in Glioblastoma—Letter [PDF]
Clinical Cancer Research, 2020 We read enthusiastically the recent article by Bagley and colleagues ([1][1]). The authors prospectively investigated plasma cell-free DNA (cfDNA) concentration and mutations in patients with glioblastoma. This is an interesting topic and we commend the authors for their efforts.
Takeshi, Takayasu +2 more
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Cell-free DNA methylome profiling by MBD-seq with ultra-low input
Epigenetics, 2022 Methylation signatures in cell-free DNA (cfDNA) have shown great sensitivity and specificity in the characterization of tumour status and classification of tumour types, as well as the response to therapy and recurrence. Currently, most cfDNA methylation
Jinyong Huang +2 more
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Dynamics of methylated cell-free DNA in the urine of non-small cell lung cancer patients
Epigenetics, 2022 High levels of methylated DNA in urine represent an emerging biomarker for non-small cell lung cancer (NSCLC) detection and are the subject of ongoing research.
Sander Bach +7 more
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Société Internationale d’Urologie Journal, 2023 None.
Manishkumar S. Patel, Liang Wang
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cfDNA in pancreatic neuroendocrine carcinoma management with Cushing’s syndrome
Endocrine Oncology, 2023 We report a case of metastatic pancreatic neuroendocrine carcinoma associated with paraneoplastic Cushing’s syndrome, successively treated with five lines of treatment (platin-etoposide, LV5FU2-dacarbazine, FOLFIRINOX, pembrolizumab, and paclitaxel) and ...
Laura Gerard +11 more
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Immunoaging – the effect of age on serum levels of NET biomarkers in men: a pilot study
International Journal of Occupational Medicine and Environmental Health, 2023 Objectives The study aimed to evaluate the impact of aging on the formation of neutrophil extracellular traps (NETs). The impaired formation of NETs is the cause of an abnormal innate immune response.
Marzena Garley +6 more
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Plasma cfDNA in Glioblastoma—Response
Clinical Cancer Research, 2020 We appreciate the interest in our study from Takayasu and colleagues. They raise important issues which were largely addressed in our article but deserve further discussion. Takayasu and colleagues question whether variants detected in plasma in our study reflect tumor somatic mutations.
Stephen J, Bagley, Erica L, Carpenter
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