Results 31 to 40 of about 23,420 (253)

Plasma cfDNA in Glioblastoma—Response

open access: yesClinical Cancer Research, 2020
We appreciate the interest in our study from Takayasu and colleagues. They raise important issues which were largely addressed in our article but deserve further discussion. Takayasu and colleagues question whether variants detected in plasma in our study reflect tumor somatic mutations.
Stephen J, Bagley, Erica L, Carpenter
openaire   +3 more sources

Genome‐wide cfDNA testing of maternal blood [PDF]

open access: yesUltrasound in Obstetrics & Gynecology, 2020
post-print 0,99 ...
Jani J. C.   +8 more
openaire   +4 more sources

NONİNVAZİV PRENATAL TARAMA cfDNA (CELL FREE DNA)

open access: yes, 2023
cfDNA hem anne (maternal cfDNA) hem de fetal-plasental ünite (fetal cfDNA) tarafından üretilmektedir. Doğum sonrası ise fetal cfDNA maternal kan dolaşımından hızla temizlenmektedir ve birkaç gün içinde maternal kanda fetal cfDNA saptanamaz.
KESKİN, Deha Denizhan
core   +1 more source

Evaluating liquid biopsies for methylomic profiling of prostate cancer

open access: yesEpigenetics, 2020
Background: Liquid biopsies offer significant potential for informing on cancer progression and therapeutic resistance via minimally invasive serial monitoring of genetic alterations.
Romina Silva   +9 more
doaj   +1 more source

Sparsely methylated mitochondrial cell free DNA released from cardiomyocytes contributes to systemic inflammatory response accompanied by atrial fibrillation

open access: yesScientific Reports, 2021
Systemic inflammation is assumed to be the consequence and the cause of atrial fibrillation (AF); however, the underlying mechanism remains unclear. We aimed to evaluate the level of cell-free DNA (cfDNA) in patients with AF and AF mimicking models, and ...
Masahiro Yamazoe   +8 more
doaj   +1 more source

The clinical value of Serum hyaluronic acid, procollagen III, N-terminal propeptide levels sST2 and cfDNA in predicting the myocardial damage in children with severe pneumonia [PDF]

open access: yesJournal of Medical Biochemistry
Background: Severe pneumonia complicated by myocardial damage is a serious condition in children, and early prediction and intervention are crucial for improving outcomes. To explore the clinical value of serum hyaluronic acid, procollagen III N-terminal
Haoran Jia   +5 more
doaj   +1 more source

Association between Levels of Total Cell-Free DNA and Development of Preeclampsia—A Literature Review

open access: yesAmerican Journal of Perinatology Reports, 2021
Objectives The aim of the study is to synthesize the evidence and evaluate the total cell-free deoxyribonucleic (cfDNA) associated with the prediction of preeclampsia (PE). Total cfDNA is constituted by both cell-free fetal DNA (cffDNA) originated mainly
Yi Wu   +5 more
doaj   +1 more source

cfDNA Sequencing: Technological Approaches and Bioinformatic Issues [PDF]

open access: yesPharmaceuticals, 2021
In the era of precision medicine, it is crucial to identify molecular alterations that will guide the therapeutic management of patients. In this context, circulating tumoral DNA (ctDNA) released by the tumor in body fluids, like blood, and carrying its molecular characteristics is becoming a powerful biomarker for non-invasive detection and monitoring
Elodie Bohers   +2 more
openaire   +5 more sources

EDTA prevents urine cfDNA degradation.

open access: yes, 2021
Technical experiment to evaluate the stability of urine cfDNA with and without the addition of EDTA. Pooled urine from a healthy volunteer was stored for 7 days with versus without 10 mM EDTA at room temperature. Urine cfDNA was extracted at days 0, 1, 3,
Jeffrey J. Szymanski (11361789)   +19 more
core   +1 more source

Genome-wide study of the effect of blood collection tubes on the cell-free DNA methylome

open access: yesEpigenetics, 2021
The methylation pattern of cfDNA, isolated from liquid biopsies, is gaining substantial interest for diagnosis and monitoring of diseases. We have evaluated the impact of type of blood collection tube and time delay between blood draw and plasma ...
Ruben Van Paemel   +7 more
doaj   +1 more source

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