Results 21 to 30 of about 19,806 (216)

The clinical value of Serum hyaluronic acid, procollagen III, N-terminal propeptide levels sST2 and cfDNA in predicting the myocardial damage in children with severe pneumonia [PDF]

Journal of Medical Biochemistry
Background: Severe pneumonia complicated by myocardial damage is a serious condition in children, and early prediction and intervention are crucial for improving outcomes. To explore the clinical value of serum hyaluronic acid, procollagen III N-terminal
Haoran Jia, Ye Liu, Tingting Zhao, Dexing Wang, Meng Du, Weiwei Wang   +5 more
doaj   +1 more source

Cell-free DNA in sports medicine: implications for clinical laboratory medicine

Journal of Laboratory Medicine, 2022
Physical activity can have a strong impact on the concentration of several promising candidate biomarkers, including cell-free DNA (cfDNA).
Neuberger Elmo W.I., Simon Perikles
doaj   +1 more source

Sparsely methylated mitochondrial cell free DNA released from cardiomyocytes contributes to systemic inflammatory response accompanied by atrial fibrillation

Scientific Reports, 2021
Systemic inflammation is assumed to be the consequence and the cause of atrial fibrillation (AF); however, the underlying mechanism remains unclear. We aimed to evaluate the level of cell-free DNA (cfDNA) in patients with AF and AF mimicking models, and ...
Masahiro Yamazoe, Tetsuo Sasano, Kensuke Ihara, Kentaro Takahashi, Wakana Nakamura, Naomi Takahashi, Hiroaki Komuro, Satomi Hamada, Tetsushi Furukawa   +8 more
doaj   +1 more source

Influence of preanalytical variables on the quality of cell-free DNA. Biobanking of cell-free DNA material

Кардиоваскулярная терапия и профилактика, 2022
The search for early disease markers and the development of diagnostic systems has recently been expanding within genomics. Genomic deoxyribonucleic acid (DNA), cell-free DNA (cfDNA) and microbiome DNA obtained from different types of samples (tissues ...
V. A. Kondratskaya, M. S. Pokrovskaya, Yu. V. Doludin, A. L. Borisova, A. S. Limonova, А. N. Meshkov, O. M. Drapkina   +6 more
doaj   +1 more source

Early markers of phenotypic heterogeneity in the induced model of systemic lupus erythematosus

Бюллетень сибирской медицины, 2018
The study aimed at evaluating the predisposition for development of different variants of SLE based on an inflammatory response in intact mice.Materials and methods.
O. P. Kolesnikova, E. V. Goiman, E. D. Gavrilova, E. N. Demchenko, V. A. Kozlov   +4 more
doaj   +1 more source

Liquid biopsy in CNS tumors: Current status & future perspectives

Indian Journal of Pathology and Microbiology, 2022
Precise classification of central nervous system (CNS) malignancies is vital for the treatment and prognostication. Identification of noninvasive markers can be of importance to guide treatment decisions and in monitoring treatment response.
Nuzhat Husain, Adil Husain, Sridhar Mishra, Pallavi Srivastava   +3 more
doaj   +1 more source

Urine-Based Cell-Free DNA Tests in Urothelial Cancer: Additional Value for Clinical Decision-Making?

Société Internationale d’Urologie Journal, 2023
None.
Lars Dyrskjøt
doaj   +1 more source

Fragmentomic cfDNA Patterns in Noninvasive Prenatal Testing and Beyond

Journal of Biomedicine and Translational Research, 2021
The release of fetoplacental cell-free DNA (cfDNA) into the maternal bloodstream opened up new avenues towards noninvasive prenatal testing (NIPT) for aneuploidies, hereditary DNA mutations and other pregnancy-related developmental disorders ...
Kavish Kohabir, Rob Wolthuis, Erik A. Sistermans   +2 more
doaj   +1 more source

Clinical relevance of circulating biomarkers in breast cancer metastasis detection: "insights from liquid biopsy technology"

Research in Pharmaceutical Sciences
Background and purpose: Breast cancer is a major global concern, especially because of high mortality linked to advanced stages. Metastasis may occur early, but current diagnostics struggle to detect small metastatic cells.
Zohreh Salimi, Rasoul Fatehifard, Mahmoud Aghaei, Mojtaba Panjehpour   +3 more
doaj   +1 more source

DNA methylation biomarkers discovered in silico detect cancer in liquid biopsies from non-small cell lung cancer patients

Epigenetics, 2020
Identification of cancer-specific methylation of DNA released by tumours can be used for non-invasive diagnostics and monitoring. We previously reported in silico identification of DNA methylation loci specifically hypermethylated in common human cancers
Lukas Vrba, Marc M. Oshiro, Samuel S. Kim, Linda L. Garland, Crystal Placencia, Daruka Mahadevan, Mark A. Nelson, Bernard W. Futscher   +7 more
doaj   +1 more source