Results 51 to 60 of about 15,575 (291)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

De aromas e perfumes, o mercado da indústria do "cheiro"

open access: yesQuímica Nova, 2012
Several flavors and fragrances (F&F) companies hold the economic leadership in the market, although not always have also the leadership in patent applications.
Marcelo Gomes Speziali
doaj   +1 more source

An Enantiospecific Synthesis of 5-epi-α-Bulnesene

open access: yesMolecules, 2023
As a result of its unique fragrance and wider role in traditional medicine, agarwood produced in Aquilaria spp. and certain other trees has been harvested to near extinction as a natural phenomenon.
Jiarui Zong, Jeremy Robertson
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Fragrances of plant origin

open access: yes, 2008
This thesis describes specifications of fragrances of plant origin, their origin and usage, methods of obtaining and ways of use them in cosmetics. Fragrances are mixtures of natural or synthetic character which give the aroma.
Koláčková, Adéla
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

The effect of curd cutting time and coagulants on the efficiency of cheesemaking

open access: yesJournal of Dairy Science
: This study evaluated the effects of curd cutting time and milk coagulant type on cheesemaking efficiency using a controlled laboratory cheesemaking model.
Giorgia Stocco   +7 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Effects of animal rennet, fermentation-produced chymosin, and microbial coagulants on bovine milk coagulation properties

open access: yesJournal of Dairy Science
: Coagulants play a crucial role in cheese production by catalyzing milk curdling, with traditional animal rennet long serving as the primary choice.
Giorgia Stocco   +7 more
doaj   +1 more source

Perfumed substances: beyond beautiful [PDF]

open access: yesRomanian Journal of Pharmaceutical Practice
Fragrance refers to any natural or synthetically ingredient intended to produce a particular scent. Perfumed components are used in a large variety of consumer products from perfumes to skin products such as creams, lotions, detergents, and various other
Gabriela TATARINGA   +2 more
doaj   +1 more source

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