Results 31 to 40 of about 13,382 (298)
Molecules, 2022 In recent years, there has been increasing interest in daily-use chemical products providing a pleasant scent. The added fragrance molecules may induce microstructural transitions of surfactant aggregates, which further affect the physical and chemical ...
Jiani Gong +9 more
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A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors
Molecules, 2020 Olfactory receptors (ORs) are expressed and active in various human tissues, including the skin. Although the sense of smell plays an important physiological role in the regulation of mood and stress, a link between olfactive compounds, ORs, and skin ...
Romain Duroux +4 more
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Cosmetics, 2022 “Seta e Ciliegia” and “Narguilé” fragrances were mixed to form a binary blend with chemically stable, non-volatile, odourless, simple bases of different lipophilicity widely used in skin care and hair care formulations, such as caprylic-capric ...
Lucrezia Di Nicolantonio +6 more
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Safety evaluation of Akkermansia massiliensis sp. nov. DSM 33459
Toxicology ReportsA novel strain of Akkermansia massiliensis sp. nov., designated as DSM 33459, was isolated from the feces of a healthy human donor. In order to fully assess the safety of this strain, following previously performed full genomic assessment, further in ...
Jeffrey Pitt +12 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Enzyme structure correlates with variant effect predictability
Computational and Structural Biotechnology JournalProtein engineering increasingly relies on machine learning models to computationally pre-screen promising novel candidates. Although machine learning approaches have proven effective, their performance on prospective screening data leaves room for ...
Floris van der Flier +12 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Safety evaluation of Butyricicoccus faecihominis DSM 34943
Toxicology ReportsA novel strain of Butyricicoccus faecihominis DSM 34943 was isolated from the feces of a healthy human donor. In order to fully assess the safety of this strain, a full genomic assessment, further in-vitro characterization and a combined in-vivo ...
Jeffrey Pitt +13 more
doaj +1 more source
Effect of fragrance use on discrimination of individual body odor
Frontiers in Psychology, 2015 Previous research suggests that artificial fragrances may be chosen to complement or enhance an individual’s body odor, rather than simply masking it, and that this may create an odor blend with an emergent quality that is perceptually distinguishable ...
Caroline eAllen +2 more
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Synthesis of odorants in flow and their applications in perfumery
Beilstein Journal of Organic Chemistry, 2022 Continuous flow technology is a key technology for sustainable manufacturing with numerous applications for the synthesis of fine chemicals. In recent years, the preparation of odorants utilizing the advantages of flow reactors received growing attention.
Merlin Kleoff +2 more
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