Results 71 to 80 of about 5,010,058 (349)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

S-Metrizability and the Wallman basis of a frame [PDF]

open access: yesCategories and General Algebraic Structures with Applications
The Wallman basis of a frame and the corresponding induced compactification was first investigated by Baboolal [2]. In this paper, we provide an intrinsic characterisation of S-metrizability in terms of the Wallman basis of a frame. Particularly, we show
Cerene Rathilal
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Einstein Frame or Jordan Frame?

open access: yesInternational Journal of Theoretical Physics, 1999
11 pages, LaTeX, no ...
Faraoni, Valerio, Gunzig, Edgard
openaire   +2 more sources

The 2008 federal intervention to stabilize Fannie Mae and Freddie Mac [PDF]

open access: yes
Fannie Mae and Freddie Mac are government-sponsored enterprises that play a central role in U.S. residential mortgage markets. In recent years, policymakers became increasingly concerned about the size and risk-taking incentives of these two institutions.
W. Scott Frame
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Framing the frame

open access: yesJudgment and Decision Making, 2007
We examined how the goal of a decision task influences the perceived positive, negative valence of the alternatives and thereby the likelihood and direction of framing effects. In Study 1 we manipulated the goal to increase, decrease or maintain the commodity in question and found that when the goal of the task was to increase the commodity, a framing ...
Todd McElroy, John J. Seta
openaire   +1 more source

Federal Home Loan Bank mortgage purchases: Implications for mortgage markets [PDF]

open access: yes
The Federal Home Loan Bank (FHLB) System is a government-sponsored enterprise created by Congress to support residential housing finance. Historically, the twelve regional wholesale banks that constitute the FHLB System have pursued this goal by making ...
W. Scott Frame
core  

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