Results 131 to 140 of about 59,619 (217)

Adaptation of translational machinery in malaria parasites to accommodate translation of poly-adenosine stretches throughout its life cycle [PDF]

, 2019
Malaria is caused by unicellular apicomplexan parasites of the ...
Djuranovic, Sergej, Djuranovic, Slavica Pavlovic, Erath, Jessey   +2 more
core   +1 more source

Encephalomyocarditis virus protein 2B* interacts with 14-3-3 proteins through a phosphorylated C-terminal binding motif

mBio
Encephalomyocarditis virus (EMCV) has been an important model RNA virus for decades. Although most of the EMCV proteins are obtained via proteolytic cleavage of a long polyprotein, 2B* is expressed from a short overlapping open reading frame via an ...
Samantha K. Nguyen, Nadine Anders, Stephen Holmes, Henry G. Barrow, Nina Lukhovitskaya, Aminu S. Jahun, Iliana Georgana, Laura G. Caller, James R. Edgar, Stephen C. Graham, Edward Emmott, Andrew E. Firth, Hazel Stewart   +12 more
doaj   +1 more source

High-Throughput Screening for a SARS-CoV-2 Frameshifting Inhibitor Using a Cell-Free Protein Synthesis System

BioTechniques
Programmed-1 ribosomal frameshifting (-1 PRF) is a translational mechanism adopted by some viruses, including SARS-CoV-2. To find a compound that can inhibit -1 PRF in SARS-CoV-2, we set up a high-throughput screening system using a HeLa cell extract ...
Kodai Machida, Rin Tanaka, Seraya Miki, Shotaro Noseda, Mayumi Yuasa-Sunagawa, Hiroaki Imataka   +5 more
doaj   +1 more source

Comprehensive analysis of yeast +1 ribosomal frameshifting unveils a novel stimulator supporting two distinct frameshifting mechanisms. [PDF]

Nucleic Acids Res
Fenton DA, Bożko M, Świrski MI, Loughran G, Yordanova MM, Kufel J, Atkins JF, Baranov PV.   +7 more
europepmc   +2 more sources

RNA G-quadruplexes promote codon repeat-associated ribosomal frameshifting in human genes. [PDF]

Nucleic Acids Res
Li X, Li Z, Zhou Y, Gong S, Chen Z, Li J, Guo M, Gu X, Li F, Wei J, Zhong T, Yin T, Li T, Xing Y, Yang X, Xu L, Lai F, Dang Y, Ren G.   +18 more
europepmc   +1 more source

Mechanisms regulating ribosomal frameshifting in decoding Ornithine Decarboxylase Antizyme mRNA [PDF]

, 2009
Kurian, Leo
core  

Integrated phenotypic screening and chemical proteomics identifies ETF1 ligands that modulate viral translation and replication. [PDF]

Proc Natl Acad Sci U S A
Kim AS, Ma K, Reinhardt CJ, Lazar DC, Ogasawara D, Shaw TM, de la Torre JC, Bailey AL, Melillo B, Teijaro JR, Cravatt BF.   +10 more
europepmc   +1 more source

Kinetics and Thermodynamics of −1 Ribosomal Frameshifting [PDF]

Biophysical Journal, 2020
Lars V. Bock, Neva Caliskan, Bee-Zen Peng, Natalia Korniy, Riccardo Belardinelli, Frank Peske, Marina V. Rodnina, Helmut Grubmueller   +7 more
openaire   +1 more source

Kinetic Traps in RNA Folding: Targeted Design of Frameshifting Element Mutants by Thermodynamic and Kinetic Analysis of the Chikungunya Virus. [PDF]

J Phys Chem B
Lee S, Schlick T.
europepmc   +1 more source

Mutations in ribosomal protein uS5 alter translation fidelity and mutagenesis in <i>Pseudomonas putida</i>. [PDF]

J Bacteriol
Jürgenstein K, Ilves H, Luhaäär C, Brauer A, Remme J, Kivisaar M.   +5 more
europepmc   +1 more source