Results 41 to 50 of about 167,794,688 (193)

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

A Bayesian Hierarchical Semiparametric Approach to Modeling Interval-Valued Panel Data

Axioms
This study proposes a Bayesian Hierarchical Semiparametric Center and Range (BHS-CRM) model to address nonlinearity and heterogeneity in interval-valued panel data.
Dengke Xu, Mengen Qin, Ruiqin Tian
doaj   +1 more source

The role of business intelligence in the analysis of customers' shopping carts to shape electronic marketing using data mining techniques [PDF]

رویکرد‌های نوین در مدیریت و بازاریابی
The purpose of this study is to investigate the role of business intelligence in customer shopping cart analysis and its impact on shaping e-marketing in businesses.
MohammadAli Azmoudeh, Maryam Hajiesmaeili, Mohsen Gharahkhani   +2 more
doaj   +1 more source

Real‐Time Monitoring of Mass and Mechanical Properties in Single Cells and Multicellular Spheroids

Advanced Science, EarlyView.
This study introduces photothermally actuated microcantilevers combined with optical microscopy to simultaneously measure morphology, mass, and mechanical properties of cellular systems in real‐time. The findings link cytoplasm‐dominated mechanical energy dissipation to the Q‐factor as a novel biophysical parameter.
Ilaria Incaviglia, Giulia E. M. Ammirati, Sophie Herzog, Tommy Krug, Nico Strohmeyer, Miguel Camacho Rufino, Matthias P. Lutolf, David A. Weitz, Daniel J. Müller   +8 more
wiley   +1 more source

Braided science field schools: cultivating professional fluency in Indigenous-centered archaeology

Frontiers in Environmental Archaeology
This paper presents a replicable model for transforming archaeological field schools into Braided Science programs that center Indigenous self-determination, robust Tribal collaboration, and integrated Cultural Resource Management (CRM) training ...
Shannon Tushingham, Shannon Tushingham, Molly Carney, Naomi Scher   +3 more
doaj   +1 more source

Presenting a model of marketing processes with data-driven innovation capabilities in B2B companies [PDF]

ارزش آفرینی در مدیریت کسب و کار
The aim of this research is to design and explain a model of marketing processes with data-driven innovation capabilities in B2B companies. The research is of a mixed type (qualitative-quantitative).
Sahar Sorkhvandi, Karim Hamdi, Hossein Vazifedust   +2 more
doaj   +1 more source

Assessing Photovoltaic Recycling Capacities and Policy Gaps in the European Union

Advanced Energy and Sustainability Research, EarlyView.
This study maps photovoltaic recycling capacity in the EU and key global regions, highlighting gaps between growing waste volumes and available infrastructure. It combines survey insights and policy analysis to identify recycling bottlenecks and offers recommendations to boost circularity in the solar sector.
Nieves Espinosa, Silvia Bobba, Cynthia E. L. Latunussa, Enrica Leccisi   +3 more
wiley   +1 more source

Real‐time monitoring of root dielectric properties for assessing crop plant damage caused by foliar application of glyphosate

Applications in Plant Sciences, EarlyView.
Abstract Premise There is a knowledge gap regarding how foliar injury and restricted water uptake can be detected by measuring root dielectric response. This pot study nondestructively evaluated the efficiency of real‐time dielectric measurement to monitor the effects of glyphosate spraying.
Imre Cseresnyés, Anna Füzy, Tünde Takács   +2 more
wiley   +1 more source

Supply chain resilience through collaborative networks and dynamic capabilities: evidence from an agri-food productive chain in Colombia

Discover Sustainability
Purpose This study examines how horizontal collaborative networks (HCNs) and collaborative risk management (CRM) practices, supported by social network analysis (SNA), contribute to strengthening supply chain resilience through the development and ...
Isabel Cristina Alzate Rendón, Sandra Milena Álvarez Gallo, Antonio Boada   +2 more
doaj   +1 more source

Adaptive imatinib regimens can mitigate cumulative toxicity while sustaining hemodynamic benefit: A model‐based simulation of the positioning imatinib for pulmonary arterial hypertension trial

British Journal of Clinical Pharmacology, EarlyView.
ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said, Robert B. de Mooij, Dian Jiao, Reitze J. Ovelgonne, Rami Biram, Juan Delgado‐SanMartin, Alexander M. K. Rothman, Sofia S. Villar, Andreas A. Roussakis, Jurjan Aman, Ron A. A. Mathôt, Eleonora L. Swart, Martin R. Wilkins, Imke H. Bartelink   +13 more
wiley   +1 more source