Results 61 to 70 of about 570,872 (304)

Doubt Versus Trust: Framing Effects of the News About the 2018 Trump‒Kim Jong Un Summit in Singapore on American College Students

open access: yesInternational Journal of Communication, 2020
This article examines the effects of trust versus doubt news frames during the 2018 denuclearization summit between the United States and North Korea in June 2018, an issue that is characterized by negative media coverage about North Korea and its leader
Chang Sup Park, Barbara K. Kaye
doaj   +2 more sources

Law, Translation, and Voice:Transformation of a Struggle for Social Justice in a Chinese Village [PDF]

open access: yes, 2011
The channeling of popular struggles through legal cases is central to the strategy of the emerging “rights defense” movement in China, linking grassroots contention with professional mediators who translate grievances into the institutional environment ...
Woodman, Sophia
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Bracketing effects on risk tolerance: Generalizability and underlying mechanisms

open access: yesJudgment and Decision Making, 2010
Research has shown that risk tolerance increases when multiple decisions and associated outcomes are presented together in a broader “bracket” rather than one at a time.
Ester Moher, Derek J. Koehler
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Public Support for Transport Reform: Does it Matter if we ‘Reduce Driving’ or ‘Shift Trips’?

open access: yesFindings, 2021
Does what the public says they want in terms of transport policy depend on how we ask? In other words, are transportation policy preferences subject to framing effects?
Kelcie Ralph   +3 more
doaj   +1 more source

The Effects of Emotional Versus Rational Message Framing on Brand Attachment and Brand Loyalty

open access: yes, 2019
The purpose of this research is to investigate the relationship among message framing in social media, brand attachment, and brand loyalty for higher education institutions.
Woinowsky, Elisa
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Latent Profile Analysis of Schizotypy and Paranormal Belief: Associations with Probabilistic Reasoning Performance

open access: yesFrontiers in Psychology, 2018
This study assessed the extent to which within-individual variation in schizotypy and paranormal belief influenced performance on probabilistic reasoning tasks.
Andrew Denovan   +3 more
doaj   +1 more source

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