Results 121 to 130 of about 38,009 (292)

A Deep Metagenomic Snapshot as a Proof‐of‐Concept for Resource Generation: Simultaneous Assembly of Host, Food, and Microbiome Genomes From Stingless Bee Larval Food

Ecology and Evolution, Volume 15, Issue 12, December 2025.
This study serves as a proof‐of‐concept, demonstrating that deep shotgun sequencing of a single complex sample—stingless bee larval food—can simultaneously generate multiple genomic resources. From this dataset, we assembled three genomes (a near‐complete bacterium, a draft host mitochondrion, and a fragmented plant chloroplast) with varying ...
Carlos Ueira‐Vieira, Ana Carolina Costa Santos, Thayane Nogueira Araújo, Solange Cristina Augusto, Natanael Borges de Avila, Ana Maria Bonetti, Anderson Rodrigues dos Santos   +6 more
wiley   +1 more source

Protective potential of outer membrane vesicles derived from a virulent strain of Francisella tularensis

Frontiers in Microbiology
Francisella tularensis secretes tubular outer membrane vesicles (OMVs) that contain a number of immunoreactive proteins as well as virulence factors.
Ivona Pavkova, Jan Bavlovic, Klara Kubelkova, Jiri Stulik, Jana Klimentova   +4 more
doaj   +1 more source

Azithromycin effectiveness against intracellular infections of Francisella

BMC Microbiology, 2010
Background Macrolide antibiotics are commonly administered for bacterial respiratory illnesses. Azithromycin (Az) is especially noted for extremely high intracellular concentrations achieved within macrophages which is far greater than the serum ...
Mann Barbara J, Qin Aiping, Hunter Lyman, Ahmad Saira, van Hoek Monique L   +4 more
doaj   +1 more source

Különböző eredetű Francisella tularensis törzsek összehasonlító vizsgálata = Comparative examination of Francisella tularensis strains isolated from different species in Hungary [PDF]

, 2012
Vizsgálataink során Magyarország közel 30 településéről összesen 67 Francisella tularensis törzset gyűjtöttünk, amely révén létrehoztunk egy hazai F. tularensis törzsgyűjteményt.
Makrai, László
core  

Francisella tularensis strain typing using multiple-locus, variable-number tandem repeat analysis [PDF]

, 2001
Francisella tularensis, the etiological agent of tularemia, is found throughout the Northern hemisphere. After analyzing the F. tularensis genomic sequence for potential variable-number tandem repeats (VNTRs), we developed a multilocus VNTR analysis ...
Abrams, Michelle, Farlow, Jason, Keim, Paul, Lytle, Michael, Smith, Kimothy L., Wong, Jane   +5 more
core   +2 more sources

Contributions of TolC Orthologs to Francisella tularensis Schu S4 Multidrug Resistance, Modulation of Host Cell Responses, and Virulence

Infection and Immunity, 2019
Francisella tularensis is a Gram-negative, facultative intracellular pathogen and the causative agent of tularemia. Previous studies with the attenuated live vaccine strain (LVS) identified a role for the outer membrane protein TolC in modulation of host
Erik J. Kopping, C. R. Doyle, Vinaya Sampath, D. Thanassi   +3 more
semanticscholar   +1 more source

Characterization of Pilin A and Thioredoxin A Mutant Strains of Acinetobacter baumannii, From a Transposon Insertion Library, for Pili Production and Virulence‐Associated Properties

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Acinetobacter baumannii transposon insertion mutant strains ΔpilA and ΔtrxA display marked reductions of surface pili. The PilA (a major pilin protein) and TrxA (thioredoxin A) deficient bacteria also show attenuation in pathogenesis including the reduction of intestinal bacterial attachment, increased phagocytic uptake and decreased mortality from ...
Jadelynn Aki, Sara B. Papp, Bayley Polk, Sean Jeffreys, Megan P. Tompkins, Anwar A. Kalalah, Mark Eppinger, Guoquan Zhang, M. N. Guentzel, James P. Chambers, Bernard P. Arulanandam, Jieh‐Juen Yu   +11 more
wiley   +1 more source

Two-Component Systems in Francisella Species

Frontiers in Cellular and Infection Microbiology, 2019
Bacteria alter gene expression in response to changes in their environment through various mechanisms that include signal transduction systems.
M. V. van Hoek, Ky V. Hoang, J. Gunn
semanticscholar   +1 more source

Border patrol gone awry: Lung NKT cell activation by Francisella tularensis exacerbates tularemia-like disease [PDF]

, 2015
The respiratory mucosa is a major site for pathogen invasion and, hence, a site requiring constant immune surveillance. The type I, semi-invariant natural killer T (NKT) cells are enriched within the lung vasculature.
Boyd, Kelli L, Cicek, Basak B, Durrant, Douglas M, Gilchuk, Pavlo, Hill, Timothy M, Joyce, Sebastian, Khanna, Kamal M, Metzger, Dennis W, Osina, Maria A   +8 more
core   +5 more sources

Multiple Acquisitions of Pathogen-Derived Francisella Endosymbionts in Soft Ticks

Genome Biology and Evolution, 2018
Bacterial endosymbionts of ticks are of interest due to their close evolutionary relationships with tick-vectored pathogens. For instance, whereas many ticks contain Francisella-like endosymbionts (FLEs), others transmit the mammalian pathogen ...
Jonathan G Gerhart, Jonathan G Gerhart, H. A. Dutcher, Amanda E. Brenner, A. S. Moses, L. Grubhoffer, Rahul Raghavan   +6 more
semanticscholar   +1 more source