Results 101 to 110 of about 27,961 (205)
Francisella recognition by inflammasomes: differences between Mice and Men
Frontiers in Cellular and Infection Microbiology, 2011 Pathogen recognition by intracellular sensors involves the assembly of a caspase-1 activation machine termed the inflammasome. Intracellular pathogens like Francisella that gain access to the cytosolic detection systems are useful tools to uncover the ...
Mikhail A Gavrilin, Mark D Wewers
doaj +1 more source
CGUG: in silico proteome and genome parsing tool for the determination of "core" and unique genes in the analysis of genomes up to ca. 1.9 Mb [PDF]
, 2009 Background Viruses and small-genome bacteria (~2 megabases and smaller) comprise a considerable population in the biosphere and are of interest to many researchers.
Padmanabhan Mahadevan +2 more
core +1 more source
The Francisella Type VI Secretion System
Frontiers in Cellular and Infection Microbiology, 2018 Francisella tularensisis subsp. tularensis is an intracellular bacterial pathogen and the causative agent of the life-threatening zoonotic disease tularemia.
Daniel L. Clemens +2 more
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Francisella tularensis Schu S4 lipopolysaccharide core sugar and o-antigen mutants are attenuated in a mouse model of tularemia [PDF]
, 2014 The virulence factors mediating Francisella pathogenesis are being investigated, with an emphasis on understanding how the organism evades innate immunity mechanisms.
Apicella, Michael A +6 more
core +2 more sources
Frontiers in Microbiology, 2016 Francisella tularensis is a Tier 1 bioterror threat and the intracellular pathogen responsible for tularemia in humans and animals. Upon entry into the host, Francisella uses multiple mechanisms to evade killing.
John S Gunn +5 more
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Identification of small RNAs in Francisella tularensis [PDF]
, 2010 Background: Regulation of bacterial gene expression by small RNAs (sRNAs) have proved to be important for many biological processes. Francisella tularensis is a highly pathogenic Gram-negative bacterium that causes the disease tularaemia in humans and ...
Alain Charbit +6 more
core +3 more sources
Проблемы особо опасных инфекций, 2016 Objective of the study is to assess diagnostic efficiency of PCR kits «Gen Francisella tularensis - REF» and «Gen Francisella tularensis - RGF», when performing analysis of biological samples from animals with experimental tularemia, as compared to other
A. M. Senichkina +3 more
doaj +1 more source
Infection of Mammalian Hepatocytes by Francisella tularensis LVS [PDF]
, 2016 Francisella tularensis, the causative agent of Tularemia, is a facultative intracellular parasite. The goal of this project is to examine how F. tularensis infects and replicates within mammalian cells, and the impact of such an infection upon the ...
Vasioutovitch, Pavel
core
PLoS ONE, 2013 Virulent Francisella tularensis ssp tularensis is an intracellular, Gram negative bacterium that causes acute lethal disease following inhalation of fewer than 15 organisms.
Amanda J Griffin +4 more
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Nramp1 and NrampB Contribute to Resistance against Francisella in Dictyostelium
Frontiers in Cellular and Infection Microbiology, 2017 The Francisella genus comprises highly pathogenic bacteria that can cause fatal disease in their vertebrate and invertebrate hosts including humans. In general, Francisella growth depends on iron availability, hence, iron homeostasis must be tightly ...
Yannick Brenz +3 more
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