Results 91 to 100 of about 6,113 (163)

Sequencing and functional analysis of a Francisella tularensis pathogenicity island

, 2008
Francisella tularensis, a Gram-negative coccobacillus, is an extremely virulent intracellular pathogen. Infection of humans with this pathogen results in tularemia, a life-threatening disease. An approximately 35 kb region found in the F.
Zhang, Na.
core  

Francisella recognition by inflammasomes: differences between Mice and Men

Frontiers in Cellular and Infection Microbiology, 2011
Pathogen recognition by intracellular sensors involves the assembly of a caspase-1 activation machine termed the inflammasome. Intracellular pathogens like Francisella that gain access to the cytosolic detection systems are useful tools to uncover the ...
Mikhail A Gavrilin, Mark D Wewers
doaj   +1 more source

Mechanisms of Francisella tularensis Intracellular Pathogenesis

, 2013
Francisella tularensis is a zoonotic intracellular pathogen and the causative agent of the debilitating febrile illness tularemia. Although natural infections by F.
Celli, Jean, Zahrt, Thomas C
core   +1 more source

Atg5-Deficient Mice Infected with Francisella tularensis LVS Demonstrate Increased Survival and Less Severe Pathology in Internal Organs

, 2020
Francisella tularensis is a highly virulent intracellular pathogen that proliferates within various cell types and can infect a multitude of animal species. Francisella escapes the phagosome rapidly after infection and reaches the host cell cytosol where
Sanja Štifter, Marečić, Valentina, Mateja Ožanič, Marina Šantić, Kelava, Ina, Mihelčić, Mirna, Ćurlin, Marija, Ožanič, Mateja, Knežević, Maša, Ina Kelava, Mirna Mihelčić, Anders Sjöstedt, Valentina Marečić, Marija Ćurlin, Sjöstedt, Anders, Štifter, Sanja, Sjöstedt, Anders,, Maša Knežević, Šantić, Marina   +18 more
core   +1 more source

Identification of genes required for secretion of the Francisella oxidative burst-inhibiting acid phosphatase AcpA

Frontiers in Microbiology, 2016
Francisella tularensis is a Tier 1 bioterror threat and the intracellular pathogen responsible for tularemia in humans and animals. Upon entry into the host, Francisella uses multiple mechanisms to evade killing.
John S Gunn, Ky Van Hoang, Carolyn G Lee, Jacob eKoopman, Jasmine eMoshiri, Haley E Adcox   +5 more
doaj   +1 more source

Characterization of Francisella sp., GM2212, the first Francisella isolate from marine fish, Atlantic cod (Gadus morhua)

, 2007
A Francisella sp., isolate GM2212(T), previously isolated from diseased farmed Atlantic cod Gadus morhua in Norway is characterized. The complete 16S rDNA, 16S-23S intergenic spacer, 23S rDNA, 23S-5S intergenic spacer, 5S rDNA, FopA, lipoprotein TUL4 ...
Friis-Møller, Alice, Nylund, Are, Karlsbakk, Egil, Ottem, Karl F, Krossøy, Bjørn   +4 more
core   +1 more source

Alternative activation of macrophages and induction of arginase are not components of pathogenesis mediated by Francisella species.

PLoS ONE, 2013
Virulent Francisella tularensis ssp tularensis is an intracellular, Gram negative bacterium that causes acute lethal disease following inhalation of fewer than 15 organisms.
Amanda J Griffin, Deborah D Crane, Tara D Wehrly, Dana P Scott, Catharine M Bosio   +4 more
doaj   +1 more source

Nramp1 and NrampB Contribute to Resistance against Francisella in Dictyostelium

Frontiers in Cellular and Infection Microbiology, 2017
The Francisella genus comprises highly pathogenic bacteria that can cause fatal disease in their vertebrate and invertebrate hosts including humans. In general, Francisella growth depends on iron availability, hence, iron homeostasis must be tightly ...
Yannick Brenz, Denise Ohnezeit, Hanne C. Winther-Larsen, Monica Hagedorn   +3 more
doaj   +1 more source

Assessment of Diagnostic Efficiency of PCR Kits «Gen Francisella tularensis - REF» and «Gen Francisella tularensis - RGF» when Analyzing Biological Samples from Animals with Experimental Tularemia

Проблемы особо опасных инфекций, 2016
Objective of the study is to assess diagnostic efficiency of PCR kits «Gen Francisella tularensis - REF» and «Gen Francisella tularensis - RGF», when performing analysis of biological samples from animals with experimental tularemia, as compared to other
A. M. Senichkina, N. A. Osina, A. S. Abdrashitova, V. G. Germanchuk   +3 more
doaj   +1 more source

Arthropod Infection Models for Francisella tularensis [PDF]

, 2018
Purpose of Review Little is known about the interactions between Francisella tularensis and arthropods. The advent of next-generation sequencing led to a better knowledge of the genetic diversity of F.
Pilo, Paola, Paola Pilo
core   +1 more source