Results 71 to 80 of about 5,673 (157)

Frataxin and the stress response

, 2010
La frataxina è una proteina mitocondriale, la cui ridotta espressione è responsabile di una malattia neurodegenerativa ereditaria, l’atassia di Friedreich (FRDA).

core  

Frataxin deficiency drives cardiac dysfunction and transcriptional dysregulation in Friedreich ataxia iPSC model. [PDF]

Cell Death Dis
Lees JG, Zhang H, Jiao L, Kong AM, Phang RJ, Li L, Su N, Bass-Stringer S, Woo HH, Mukhtar AS, Pébay A, Dottori M, Corben L, Delatycki M, Peverill R, Wilcox S, Choi J, Pullin JM, McCarthy D, Napierala JS, Napierala M, Lim SY.   +21 more
europepmc   +1 more source

Reply to “Frataxin fracas” [PDF]

Nature Genetics, 1997
Susan Chamberlain, Mark Pook, Jaime Carvajal, Kitm Doudney, Renate Hillermann   +4 more
openaire   +1 more source

Therapeutic activity of a hematopoietic stem cell-delivered cell-penetrating frataxin in Friedreich's ataxia models. [PDF]

Cell Rep Med
Pido-Lopez J, Moula SE, Shaban E, Stamatiou K, Critchley BJ, Whittaker TE, Svensson S, Anjomani-Virmouni S, Kalef-Ezra E, Carr L, Hassel J, Thrasher AJ, Kurian MA, Blair IA, Rojsajjakul T, Santilli G, Sala A.   +16 more
europepmc   +1 more source

Recent developments in Friedreich's ataxia: a state-of-the-art review. [PDF]

Brain Commun
Chapman LR, Mortiboys H, Shaw PJ.
europepmc   +1 more source

Peripheral frataxin levels govern long-term clinical progression in Friedreich ataxia. [PDF]

BMJ Neurol Open
Rummey C, Blair IA, Mesaros C, Rojsajjakul T, Dong Y, Wilmot G, Zesiewicz T, Mathews K, Hoyle JC, Seeberger L, Corben LA, Delatycki MB, Finkel RS, Roxburgh RH, Duquette A, Yoon G, Gomez CM, Subramony SH, Perlman S, Mccormack S, Lynch DR.   +20 more
europepmc   +1 more source

Iron coordination and protein-protein interactions of the protein frataxin

, 2014
Frataxin is a mitochondrial iron metallochaperone that transports ferrous iron to proteins that require it for function. This dissertation research explores the iron binding properties of human frataxin and how frataxin interacts with the mitochondrial ...
Frantom, Patrick, Marcus, Stevan, Gentry-Dye, Leslie, Busenlehner, Laura S., Woski, Stephen, University of Alabama. Dept. of Chemistry, Street, Shane   +6 more
core  

Hypomagnetic Field Exposure Alters Iron-Sulfur Homeostasis and Oxidative Balance in a Frataxin-Deficient Insect System. [PDF]

Insects
Kang HM, Li B, Yan S, Zhang LL, Wan GJ, Zhang JZ, Pan WD.   +6 more
europepmc   +1 more source

Longitudinal analysis shows GAA1 length and baseline clinical status as robust predictors of progression in Friedreich ataxia. [PDF]

J Neurol
Manrique L, Martínez-Dubarbie F, Pelayo-Negro AL, Benitez-Calle N, Sanchez-Pelaez MV, Cota-Gonzalez D, Loza R, Martinez-Díaz R, Irure-Ventura J, Sanchez-Quintana C, Sanchez I, Matilla-Dueñas A, Infante J.   +12 more
europepmc   +1 more source

Hypomagnetic Fields Influence the Developmental Duration, Fecundity and Temperature Stress Resistance of <i>Drosophila melanogaster</i> via Frataxin-Associated Traits. [PDF]

Biology (Basel)
Kang H, Wan G, Zhang J, Pan W.
europepmc   +1 more source